Smith 1973b.
Methods | Setting: UK, hospital outpatient clinic Length of intervention period: 2 weeks Randomisation: yes, method not stated Allocation concealment: not stated Design: crossover, no washout Masking: double blind Excluded: not stated Withdrawals: stated Baseline characteristics: not stated regarding baseline spirometry or doses of oral steroids used Jadad score: 3 | |
Participants | 40 children/adults: 26M 14F Age range: 5 to 20 years Inclusion criteria: Asthma requiring maintenance OCS for control Exclusion criteria: Not stated | |
Interventions | BDP: 50 mcg 2 pfs 4x daily (400/d) Placebo: 2 pfs 4xdaily Delivery device: MDI |
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Outcomes | % change in FEV1 Patient preference for BDP Physician preference for BDP Daily asthma symptom score | |
Notes | No reply from author to clarify details of method of randomisation. No details of patient baseline characteristics in terms of spirometry or doses of oral steroids used. No details regarding criteria used by physicians to assess which treatment was "better". | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |