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. 2005 Jan 24;2005(1):CD002738. doi: 10.1002/14651858.CD002738.pub2

Smith 1973b.

Methods Setting: UK, hospital outpatient clinic 
 Length of intervention period: 2 weeks 
 Randomisation: yes, method not stated 
 Allocation concealment: not stated 
 Design: crossover, no washout 
 Masking: double blind 
 Excluded: not stated 
 Withdrawals: stated 
 Baseline characteristics: not stated regarding baseline spirometry or doses of oral steroids used 
 Jadad score: 3
Participants 40 children/adults: 26M 14F 
 Age range: 5 to 20 years 
 Inclusion criteria: 
 Asthma requiring maintenance OCS for control 
 Exclusion criteria: 
 Not stated
Interventions BDP: 50 mcg 2 pfs 4x daily (400/d)
Placebo: 2 pfs 4xdaily
Delivery device: MDI
Outcomes % change in FEV1 
 Patient preference for BDP 
 Physician preference for BDP 
 Daily asthma symptom score
Notes No reply from author to clarify details of method of randomisation. 
 No details of patient baseline characteristics in terms of spirometry or doses of oral steroids used. 
 No details regarding criteria used by physicians to assess which treatment was "better".
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear
HHS Vulnerability Disclosure