Figure 1.

First and second renal biopsy findings by light microscopy and electron microscopy. A and B represent first biopsy (PAS stain) which show nodular glomerular mesangial sclerosis and relatively mild hypercellularity with Kimmelstiel Wilson nodule formation (arrow)(A), as well as segmental scar formation (B) with adhesion to the Bowman's capsule and associated foam cells (arrow). C and D represent second biopsy (PAS stain) which show similar histology findings to the first biopsy with nodular glomerulosclerosis (C) in most sampled glomeruli and focal segmental glomerulosclerosis (D). E and F are electron microscopic findings on the first biopsy which reveals over 90% of podocyte foot process effacement, no electron dense immune type deposits along the capillary loops or other places, and diffuse thickening of the glomerular basement membrane.