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Cytotoxicity of ACAi-028, PF74, and ebselen against various cell linesa
| Cell line | CC50 (μM) of: |
||
|---|---|---|---|
| ACAi-028 | PF74 | Ebselen | |
| Li-7 (hepatocyte) | >100 | >100 | >20 |
| HLE (hepatocyte) | 72.3 | >100 | >20 |
| HEK293 (kidney) | 62.6 | >100 | >20 |
| MT-4 (lymphocyte) | >100 | >100 | >20 |
| MT-2 (lymphocyte) | 86.6 | >100 | >20 |
| PBMC | >100 | n.d. | n.d. |
Cells were incubated with the respective compounds for 1 week before cytotoxicity was quantified using the MTT assay.
