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In vivo change in log10 bacterial burden from 0 h in animals treated with sham control, ceftazidime 2 g every 8 h (q8h) by 2-h infusion human-simulated regimen (HSR), cefepime 1 g q8h by 2-h infusion HSR, or cefepime 2 g q8h by 2-h infusion HSR in the murine thigh infection model.
