Table 1.

Typical Systemic Therapeutic Options for the Three Major Molecular Subtypes of Breast Cancer

	Luminal ER-Positive	HER2-Enriched	Basal-Like (or Triple-Negative)
Endocrine therapy	For all patients	For patients with ER-positive tumors	N/A
HER2-targeted therapy	N/A	For all patients	N/A
Chemotherapy	For certain patients	For all patients	For all patients

Abbreviations: ER, estrogen receptor; HER2, human epidermal growth factor receptor 2.