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. 2021 Sep 7;17(9):e1009488. doi: 10.1371/journal.ppat.1009488

Fig 3. pH-dependence of LASV GPC-mediated cell-cell fusion.

Fig 3

(A) Fusion between COS7 cells transfected with LASV GPC and HEK293T cells mock-transfected or transfected with LAMP1mut was triggered by exposure to buffers of different acidity for 20 min at 37°C (optimal trigger). The results are means and SEM from three independent experiments. (B) pH-dependence of fusion, using the protocol described in panel A, was measured between LASV GPC-expressing COS7 cells and plain QT6 cells or QT6 cells transfected with LAMP1mut. The results are means and SEM from three independent experiments. *, p<0.05; **, p<0.01, ***, p<0.001.