Table 4.
Adverse events (N = 30)
| G1 | G2 | G3 | G4 | Grade ≥ 1 | Percentage | Grade ≥ 3 | Percentage | |
|---|---|---|---|---|---|---|---|---|
| Nausea | 16 | 4 | 0 | 0 | 20 | 66.7 | 0 | 0 |
| Fatigue | 10 | 8 | 0 | 0 | 18 | 60 | 0 | 0 |
| Leucopenia | 2 | 2 | 3 | 1 | 7 | 23.3 | 4 | 13.3 |
| Neutropenia | 2 | 2 | 4 | 2 | 10 | 33.3 | 6 | 20 |
| Vomiting | 9 | 3 | 0 | 0 | 12 | 40 | 0 | 0 |
| Anemia | 2 | 1 | 1 | 0 | 4 | 13.3 | 1 | 3.3 |
| Thrombocytopenia | 2 | 1 | 1 | 0 | 4 | 13.3 | 1 | 3.3 |
| Transaminase increased | 3 | 2 | 0 | 0 | 5 | 16.7 | 0 | 0 |
| Diarrhea | 5 | 3 | 0 | 0 | 8 | 26.7 | 0 | 0 |
| Cough | 5 | 1 | 1 | 0 | 7 | 23.3 | 1 | 3.3 |
| Limb edema | 2 | 1 | 0 | 0 | 3 | 10 | 0 | 0 |
| Febrile neutropenia | 0 | 0 | 2 | 0 | 2 | 6.7 | 2 | 6.7 |
| Hypokalemia | 2 | 1 | 0 | 0 | 3 | 10 | 0 | 0 |
| Hypothyroidism | 2 | 1 | 0 | 0 | 3 | 10 | 0 | 0 |
| Hyperthyroidism | 1 | 1 | 0 | 0 | 2 | 6.7 | 0 | 0 |