Table 3.
Response to first-line chemotherapy prior to inclusion according to FGFR2 fusions status
| Responses | FGFR2 fusions | Total | ||
|---|---|---|---|---|
| Positive (n = 4) | Negative (n = 77) | Indeterminate (n = 3) | ||
| Complete response (CR) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) |
| Partial response (PR) | 0 (0.0%) | 11 (14.3%) | 1 (33.3%) | 12 (14.3%) |
| Stable disease (SD) | 1 (25.0%) | 25 (32.5%) | 1 (33.3%) | 27 (32.1%) |
| Non-CR/Non-PD | 0 (0.0%) | 1 (1.3%) | 0 (0.0%) | 1 (1.2%) |
| Progressive disease (PD) | 1 (25.0%) | 14 (18.2%) | 0 (0.0%) | 15 (17.9%) |
| Not evaluable (NE) | 2 (50.0%) | 26 (33.8%) | 1 (33.3%) | 29 (34.5%) |
| Response rate (CR + PR) | 0 (0.0%) | 11 (14.3%) | 1 (33.3%) | 12 (14.3%) |
| 95% confidence interval (%) | [0.0, 49.0] | [8.2, 23.8] | [6.1, 79.2] | [8.4, 23.3] |
| Disease control rate (CR + PR + SD + Non-CR/Non-PD) | 1 (25.0%) | 37 (48.1%) | 2 (66.7%) | 40 (47.6%) |
| 95% confidence interval (%) | [4.6, 69.9] | [37.3, 59.0] | [20.8, 93.9] | [37.3, 58.2] |
Analysis set: FLCS.