Table 1. Red blood cell analysis of Balb-c nude mice bearing breast tumor.
| Red cells
(106/mm3) |
Hemoglobin
(g/dL) |
Hematocrit (%) | MCV (fl) | MCH (pg) | MCHC (g/dL) | RDW (%) | |
|---|---|---|---|---|---|---|---|
| CTL Healthy | 9.48 ± 0.65 | 14.50 ± 0.81 | 49.26 ± 2.73 | 52.52 ± 0.69 | 15.46 ± 0.22 | 29.44 ± 0.32 | 19.15 ± 0.67 |
| Vehicle | 9.90 ± 0.31 | 14.60 ± 0.23 | 51.09 ± 1.62** | 51.58 ± 0.43 | 14.74 ± 0.31 | 28.57 ± 0.60 | 20.06 ± 0.32 |
| 4bt (50 mg/Kg) | 9.38 ± 0.23 | 14.23 ± 0.4 | 48.53 ± 1.62 | 51.75 ± 0.88 | 15.18 ± 0.23 | 29.32 ± 0.45 | 19.68 ± 0.40 |
| 4bc (50 mg/Kg) | 9.29 ± 0.3 | 14.07 ± 0.51 | 47.43 ± 2.06** | 51.07 ± 081* | 15.13 ± 0.4 | 29.67 ± 0.68 | 19.65 ± 0.56 |
| 4bt (80 mg/Kg) | 8.97 ± 0.34 | 13.56 ± 0.56 | 45.13 ± 1.83**** | 50.30 ± 0.16*** | 15.13 ± 0.21 | 30.03 ± 0.37 | 19.70 ± 0.22 |
| 4bc (80 mg/Kg) | 9.75 ± 0.4 | 14.57 ± 0.56 | 48.77 ± 2.11 | 50.04 ± 0.68**** | 14.94 ± 0.12 | 29.88 ± 0.47 | 20.34 ± 0.41 |
| 4bt+4bc (25 mg/kg) | 9.57 ± 0.62 | 14.48 ± 0.84 | 49.23 ± 2.63 | 51.48 ± 0.71 | 15.14 ± 0.29 | 29.39 ± 0.54 | 20.00 ± 0.89 |
| Paclitaxel 20 mg/kg | 8.15 ± 0.08 | 12.80 ± 0.14* | 42.56 ± 0.62**** | 52.23 ± 0.42 | 15.73 ± 0.05 | 30.07 ± 0.12 | 22.85 ± 0.98**** |
| AC-T | 8.72 ± 0.15 | 13.42 ± 0.28 | 44.57 ± 0.99**** | 51.10 ± 0.71 | 15.40 ± 0.18 | 30.10 ± 0.46 | 21.22 ± 0.13** |
| AC-4bt | 9.23 ± 0.49 | 14.06 ± 0.80 | 46.94 ± 2.35*** | 50.84 ± 0.71* | 15.24 ± 0.10 | 29.98 ± 0.36 | 21.46 ± 0.36*** |
MCV: Mean corpuscular volume; MCH: Mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; RDW: red cell distribution width. Data represent mean ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 as compared to control group (CTL Healthy).