Table 2. Biochemical analysis of Balb-c nude mice bearing breast tumor.

	Creatinine (mg/dL)	LDH (U/L)	ALP (U/L)	GGT (U/L)	AST (UI/L)	ALT (UI/L)	Urea (mg/dL)
CTL Healthy	< 0,2	673.20 ± 154.01	109.40 ± 8.24	1	115.00 ± 16.70	30.00 ± 2.45	68.80 ± 7.47
Vehicle	< 0,2	527.00 ± 118.82***	79.00 ± 12.44	1.20 ± 0.40	98.40 ± 26.31	25.00 ± 1.10	56.60 ± 4.88
4bt (50 mg/Kg)	< 0,2	677.60 ± 84.90	63.40 ± 2.42	1.00 ± 0.63	152.00 ± 37.35	28.60 ± 3.67	60.00 ± 4.15
4bc (50 mg/Kg)	< 0,2	712.75 ± 107.63	67.75 ± 8.47	1.00 ± 0.71	132.50 ± 26.69	27.50 ± 5.89	53.50 ± 4.92
4bt (80 mg/Kg)	< 0,2	552.20 ± 133.08 *	75.80 ± 10.93	< 1	150.00 ± 40.31	34.20 ±2.64	68.40 ± 4.76
4bc (80 mg/Kg)	< 0,2	537.80 ± 122.98**	93.80 ± 14.69	1	118.80 ± 29.38	29.40 ± 4.50	63.60 ± 3.14
4bt+4bc (25 mg/kg)	< 0,2	705.80 ± 331.33	73.80 ± 10.89	1.60 ± 2.25	218.00 ± 139.16*	41.60 ± 20.95	53.00 ± 4.38
Paclitaxel (20 mg/kg)	< 0,2	464.50 ± 50.5****	86.50 ± 10.5	< 1	98.50 ± 21.50	21.50 ± 1.50	59.00 ± 2.00
AC-T	< 0,2	424.00 ± 70.21****	77.00 ± 6.60	< 1	108.75 ± 19.18	21.50 ± 1.80	54.25 ± 1.92
AC-4bt	< 0,2	398.20 ± 98.17****	93.40 ± 9.99	< 1	100.80 ± 19.96	28.20 ± 4.12	60.60 ± 7.17

LDH: Lactate dehydrogenase; ALP: alkaline phosphatase; GGT: Gamma-glutamyl transferase; AST: aspartate aminotransferase; ALT: alanine transaminase. Data represent mean ± SEM. ^* p < 0.05, ^** p < 0.01, ^*** p < 0.001, ^**** p < 0.0001 as compared to control group (CTL Healthy).