Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 2;59(4):81. doi: 10.3892/ijo.2021.5260

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Huang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Anti-miR-93 promotes cell cycle arrest and the apoptosis of AML cells. The expression of miR-93 was upregulated in THP-1 cells and downregulated in HL60 cells. (A) Cell cycle distribution was measured by flow cytometry. (B) Relative cell apoptosis was detected by flow cytometry. (C) Levels of the cycle-related proteins, p21 and cyclin D1, and the apoptosis-related proteins, caspase3, Bax and Bcl-2, were detected by western blot analysis. (D) Representative images of Hoechst 33258 staining. Each experiment was performed 3 times, independently. Data are presented as the means ± standard deviation. Data in (A-C) were analyzed by one-way ANOVA, followed by Tukey's multiple comparisons test. ^*P<0.05, compared with the control group; ^#P<0.05, compared with the oe-NC or anti-NC group. miR-93, microRNA-93; NC, negative control; AML, acute myeloid leukemia.