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. 2021 Sep 7;97(10):e975–e987. doi: 10.1212/WNL.0000000000012463

Figure 1. Patient Immunoglobulin (Ig) Recognized Lipoprotein Receptor-Related Protein 4 (LRP4) and Agrin and Labeled the Neuromuscular Junction (NMJ).

Figure 1

(A) The patient Ig recognized human LRP4-ECD-Myc protein. (B) The patient Ig recognized the endogenous Lrp4 protein in C2C12. (C) The patient Ig recognized Flag-agrin-LG123 protein (a C-terminal 110-KDa fragment). (D) Staining the NMJ with the patient Ig, but not healthy Ig. Scale bars:10 μm. IP = immunoprecipitation.