Table 1.
Demographic and Clinical Characteristics of the Participants at Baseline.*
| Characteristic | Overall (N = 4566) | Cabotegravir Group (N = 2282) | TDF-FTC Group (N = 2284) |
|---|---|---|---|
| Cohort — no. (%) | |||
| MSM | 3992 (87.4) | 2013 (88.2) | 1979 (86.6) |
| Transgender women who have sex with men | 570 (12.5) | 266 (11.7) | 304 (13.3) |
| Participant preferred not to answer | 4 (0.1) | 3 (0.1) | 1 (<0.1) |
| Age category — no. (%) | |||
| 18–29yr | 3080 (67.5) | 1572 (68.9) | 1508 (66.0) |
| 30–39yr | 1048 (23.0) | 498 (21.8) | 550 (24.1) |
| 40–49 yr | 315 (6.9) | 145 (6.4) | 170 (7.4) |
| 50–59yr | 110 (2.4) | 60 (2.6) | 50 (2.2) |
| ≥60 yr | 13 (0.3) | 7 (0.3) | 6 (0.3) |
| Median age (IQR) — yr | 26 (22–32) | 26 (22–32) | 26 (22–32) |
| Latinx or Hispanic ethnic group, according to geographic region — no./total no. (%)† | |||
| United States | |||
| Yes | 303/1698 (17.8) | 149/849 (17.6) | 154/849 (18.1) |
| No | 1394/1698 (82.1) | 700/849 (82.4) | 694/849 (81.7) |
| Data missing | 1/1698 (<0.1) | 0 | 1/849 (0.1) |
| Latin America | |||
| Yes | 1806/1964 (92.0) | 894/980 (91.2) | 912/984 (92.7) |
| No | 158/1964 (8.0) | 86/980 (8.8) | 72/984 (7.3) |
| SexPro score, according to geographic region — no./total no. (%)‡ | |||
| United States | |||
| ≤16 | 1447/1698 (85.2) | 729/849 (85.9) | 718/849 (84.6) |
| >16 | 251/1698 (14.8) | 120/849 (14.1) | 131/849 (15.4) |
| Latin America | |||
| ≤16 | 1675/1964 (85.3) | 825/980 (84.2) | 850/984 (86.4) |
| >16 | 289/1964 (14.7) | 155/980 (15.8) | 134/984 (13.6) |
| Geographic region — no. (%) | |||
| United States | 1698 (37.2) | 849 (37.2) | 849 (37.2) |
| Latin America | |||
| Argentina | 337 (7.4) | 169 (7.4) | 168 (7.4) |
| Brazil | 796 (17.4) | 395 (17.3) | 401 (17.6) |
| Peru | 831 (18.2) | 416 (18.2) | 415 (18.2) |
| Asia | |||
| Thailand | 553 (12.1) | 275 (12.1) | 278 (12.2) |
| Vietnam | 199 (4.4) | 100 (4.4) | 99 (4.3) |
| Africa | 152 (3.3) | 78 (3.4) | 74 (3.2) |
| Race, according to geographic region — no./total no. (%)† | |||
| United States | |||
| Black | 845/1698 (49.8) | 411/849 (48.4) | 434/849 (51.1) |
| Non-Black | 851/1698 (50.1) | 437/849 (51.5) | 414/849 (48.8) |
| Data missing | 2/1698 (0.1) | 1/849 (0.1) | 1/849 (0.1) |
| Latin America | |||
| Black or mixed | 392/1964 (20.0) | 198/980 (20.2) | 194/984 (19.7) |
| Indigenous | 862/1964 (43.9) | 435/980 (44.4) | 427/984 (43.4) |
| Asian | 8/1964 (0.4) | 6/980 (0.6) | 2/984 (0.2) |
| White | 659/1964 (33.6) | 319/980 (32.6) | 340/984 (34.6) |
| Other | 43/1964 (2.2) | 22/980 (2.2) | 21/984 (2.1) |
| Asia | |||
| Asian | 749/752 (99.6) | 374/375 (99.7) | 375/377 (99.5) |
| Other | 3/752 (0.4) | 1/375 (0.3) | 2/377 (0.5) |
| Africa | |||
| Black | 119/152 (78.3) | 62/78 (79.5) | 57/74 (77.0) |
| Other | 5/152 (3.3) | 2/78 (2.6) | 3/74 (4.1) |
| Mixed | 28/152 (18.4) | 14/78 (17.9) | 14/74 (18.9) |
| Marital status — no. (%) | |||
| Married, civil union, or legal partnership | 177 (3.9) | 79 (3.5) | 98 (4.3) |
| Living with primary or main partner | 292 (6.4) | 138 (6) | 154 (6.7) |
| Have primary or main partner, not living together | 335 (7.3) | 171 (7.5) | 164 (7.2) |
| Single, divorced, or widowed | 3751 (82.2) | 1888 (82.7) | 1863 (81.6) |
| Other | 11 (0.2) | 6 (0.3) | 5 (0.2) |
| Educational level — no. (%) | |||
| No schooling | 8 (0.2) | 2 (0.1) | 6 (0.3) |
| Primary school | 70 (1.5) | 28 (1.2) | 42 (1.8) |
| Secondary school | 1012 (22.2) | 490 (21.5) | 522 (22.9) |
| Technical training | 375 (8.2) | 187 (8.2) | 188 (8.2) |
| College or university or higher | 3101 (67.9) | 1575 (69.0) | 1526 (66.8) |
Percentages may not sum to 100 because of rounding. IQR denotes interquartile range, MSM men who have sex with men, and TDF–FTC tenofovir disoproxil fumarate–emtricitabine.
Race and ethnic group were reported by the participant.
SexPro is a Web-based tool that provides a sexual health promotion score. It is validated to predict the 6-month risk of HIV acquisition on the basis of sexual behaviors, sexual networks, substance use, history of sexually transmitted infections, race or ethnic group (United States only), and age. Additional background on the SexPro tool is provided in the protocol. Scores range from 1 to 20, with higher scores indicating a lower risk of acquiring HIV infection.