Table 2.
The univariate Cox analysis of TNF family genes in the TCGA cohort.
| Gene symbol | HR | Aliases | Family | HR.95L | HR.95H | P value |
|---|---|---|---|---|---|---|
| CD27 | 0.9709 | TNFRSF7 | TNFRSF | 0.8151 | 1.1565 | 0.7406 |
| CD40 | 1.0949 | TNFRSF5 | TNFRSF | 0.9181 | 1.3056 | 0.3130 |
| CD40LG | 1.0877 | TNFSF5, CD154 | TNFSF | 0.7844 | 1.5083 | 0.6142 |
| CD70 | 1.0377 | TNFSF7, CD27L | TNFSF | 0.8573 | 1.2560 | 0.7044 |
| EDA | 0.9661 | EDA-A1, EDA-A2 | TNFSF | 0.7994 | 1.1675 | 0.7208 |
| EDA2R | 0.9405 | TNFRSF27, XEDAR | TNFRSF | 0.7224 | 1.2243 | 0.6484 |
| EDAR | 1.0668 | EDA-A1R | TNFRSF | 0.9437 | 1.2060 | 0.3010 |
| FAS | 0.8419 | TNFRSF6, CD95 | TNFRSF | 0.6874 | 1.0311 | 0.0962 |
| FASLG | 0.9453 | TNFSF6, CD95-L | TNFSF | 0.6999 | 1.2766 | 0.7135 |
| LTA | 0.9417 | TNFSF1 | TNFSF | 0.6381 | 1.3896 | 0.7621 |
| LTB | 1.0080 | TNFSF3 | TNFSF | 0.8389 | 1.2112 | 0.9322 |
| LTBR | 1.4905 | TNFRSF3 | TNFRSF | 0.9610 | 2.3117 | 0.0747 |
| NGFR | 1.1845 | TNFRSF16, CD271 | TNFRSF | 0.9744 | 1.4399 | 0.0891 |
| RELT | 1.0834 | TNFRSF19L | TNFRSF | 0.7789 | 1.5068 | 0.6343 |
| TNF | 0.8812 | TNFSF2, TNFA | TNFSF | 0.6434 | 1.2069 | 0.4305 |
| TNFRSF10A | 0.8024 | TRAILR1, CD261 | TNFRSF | 0.6140 | 1.0488 | 0.1071 |
| TNFRSF10B | 0.7799 | TRAILR2, CD262 | TNFRSF | 0.5935 | 1.0248 | 0.0744 |
| TNFRSF10C | 0.7389 | TRAILR3, CD263 | TNFRSF | 0.5563 | 0.9814 | 0.0367 |
| TNFRSF10D | 0.9766 | TRAILR4, CD264 | TNFRSF | 0.7621 | 1.2514 | 0.8515 |
| TNFRSF11A | 0.7898 | RANK, CD265 | TNFRSF | 0.6530 | 0.9554 | 0.0151 |
| TNFRSF11B | 0.9560 | OPG | TNFRSF | 0.8222 | 1.1115 | 0.5582 |
| TNFRSF12A | 1.0208 | FN14, TWEAKR, CD266 | TNFRSF | 0.8196 | 1.2715 | 0.8542 |
| TNFRSF13B | 0.9264 | TACI, TNFRSF14B, CD267 | TNFRSF | 0.5875 | 1.4606 | 0.7420 |
| TNFRSF13C | 1.1481 | BAFFR, CD268 | TNFRSF | 0.8683 | 1.5180 | 0.3326 |
| TNFRSF14 | 1.3445 | LIGHTR, HVEM, CD270 | TNFRSF | 0.9390 | 1.9252 | 0.1061 |
| TNFRSF17 | 0.8806 | BCMA, TNFRSF13A, CD269 | TNFRSF | 0.7463 | 1.0390 | 0.1318 |
| TNFRSF18 | 1.0049 | GITR, AITR, CD357 | TNFRSF | 0.8154 | 1.2386 | 0.9631 |
| TNFRSF19 | 1.1917 | TROY, TAJ | TNFRSF | 1.0162 | 1.3976 | 0.0309 |
| TNFRSF1A | 1.1784 | TNFR1, CD120A | TNFRSF | 0.7865 | 1.7654 | 0.4262 |
| TNFRSF1B | 0.8724 | TNFR2, CD120B | TNFRSF | 0.6804 | 1.1186 | 0.2819 |
| TNFRSF21 | 1.1121 | DR6, CD358 | TNFRSF | 0.7778 | 1.5902 | 0.5602 |
| TNFRSF25 | 1.3221 | DR3, TNFRSF12 | TNFRSF | 1.0482 | 1.6675 | 0.0184 |
| TNFRSF4 | 1.0445 | OX40, CD134 | TNFRSF | 0.8318 | 1.3116 | 0.7078 |
| TNFRSF6B | NA | DCR3 | TNFRSF | NA | NA | NA |
| TNFRSF8 | 0.9705 | CD30 | TNFRSF | 0.6332 | 1.4876 | 0.8908 |
| TNFRSF9 | 0.8403 | 4-1BB, CD137, ILA | TNFRSF | 0.6078 | 1.1616 | 0.2922 |
| TNFSF10 | 0.9383 | TRAIL, CD253 | TNFSF | 0.7388 | 1.1917 | 0.6018 |
| TNFSF11 | 0.8209 | RANKL, CD254 | TNFSF | 0.6601 | 1.0207 | 0.0758 |
| TNFSF12 | 1.1672 | TWEAK | TNFSF | 0.9247 | 1.4732 | 0.1931 |
| TNFSF13 | 1.0137 | APRIL, CD256 | TNFSF | 0.8102 | 1.2683 | 0.9054 |
| TNFSF13B | 1.0583 | BAFF, CD257 | TNFSF | 0.8784 | 1.2750 | 0.5510 |
| TNFSF14 | 0.8514 | LIGHT, HVEML, CD258 | TNFSF | 0.5787 | 1.2526 | 0.4141 |
| TNFSF15 | 0.9451 | TL1A | TNFSF | 0.7111 | 1.2563 | 0.6976 |
| TNFSF18 | 0.8249 | GITRL | TNFSF | 0.5191 | 1.3108 | 0.4152 |
| TNFSF4 | 0.9764 | OX40L, CD134L, CD252 | TNFSF | 0.7877 | 1.2104 | 0.8278 |
| TNFSF8 | 1.1121 | CD30L, CD153 | TNFSF | 0.7984 | 1.5490 | 0.5299 |
| TNFSF9 | 0.9408 | 4-1BB-L, CD137L | TNFSF | 0.8274 | 1.0698 | 0.3521 |