Table 2.

Effect of dADSCs in PNI animal models.

Stem cell characteristics	Cell markers	Animal/nerve	Experimental model	Delivery system	Contribution to PNI regeneration	Reference
Neuronally differentiated ADSCs	βIII-tubulin	Rat sciatic nerve	10 mm nerve gap	Aligned PBHV nanofiber nerve scaffold	Improved motor functional and histological recovery	[106]
ADSCs-SC-like cells	GFAP, S100	Rat sciatic nerve	10 mm nerve gap	Acellular nerve allograft	Enhanced walking-track and electrophysiological result	[42]
Differentiated ADSCs	GFAP, S100	Rat sciatic nerve	15 mm nerve gap	Acellular nerve	Augmented histological and electrophysiological recovery	[107]
ADSCs-SC-like cells	S100, NGFR p75	Rat sciatic nerve	10 mm nerve gap	Biodegradable chitin conduit	Promoted motor functional and histological recovery	[108]
Differentiated ADSCs	S100, GFAP, p75	Rat sciatic nerve injury	15 mm nerve gap	NeuraWrap™ filled with EngNT-dADSC sheets	Supported neuronal regeneration in regard to myelination thickness and number of axons	[109]
Differentiated ADSCs	GFAP, S100	Rat sciatic nerve injury	15 mm nerve gap	PGA-c tube	Improved myelin formation and functional recovery	[110]
Differentiated ADSCs	GFAP, S100	Rat sciatic nerve injury	10 mm nerve gap	GGT nerve conduit	Promoted SFI, electrophysiological recovery, and gained equally result with autologous in histological analysis	[111]
Differentiated ADSCs	GFAP, βIII-tubulin	Rat facial nerve	8 mm	Decellularized allogeneic artery conduits	Promoted nerve regeneration and functional restoration.	[112]
Differentiated ADSCs	GFAP, S100, p75	Rat sciatic nerve injury	10 mm nerve gap	PHB tube filled with fibrin glue	Increased axon myelination and functional recovery	[113]