Skip to main content
. 2021 Aug 18;13(8):e17289. doi: 10.7759/cureus.17289

Table 1. Review of immunohistochemistry studies of malignant proliferating trichilemmal tumors.

Abbreviations: >, greater than; CD, cluster of differentiation; CK, cytokeratin; CR, current report; F, female; IHC, immunohistochemistry; M, male; NS, not stated; PHH3: phosphohistone H3; UEA-I: Ulex europaeus agglutinin-I

aImmunohistochemistry on the initial tumor showed 25% positivity for Ki-67. At three-year and four-year follow-up, the tumor showed 40% and 60% positivity for Ki-67, respectively.

Case Patient Characteristics (Age, Sex) Results of IHC Reference
1 NS, NS Positive for p53 Urano et al., 1992 [8]
2 57, M Weakly positive for UEA-I Ko et al., 1996 [9]
3 95, M Weakly positive for UEA-I Ko et al., 1996 [9]
4 56, F Negative for UEA-I Ko et al., 1996 [9]
5 32, M Increasing Ki-67 positivity as the extent of the tumor advanceda Park et al., 1997 [10]
6 64, F Negative for CD34 Herrero et al., 1998 [11]
7 53, M Negative for CD34 Herrero et al., 1998 [11]
8 66, F Negative for CD34 Herrero et al., 1998 [11]
9 32, M Positive for chromogranin A; positive for p53 Nakai et al., 2008 [12]
10 58, F <1% CD34 reactivity; positive for Ki-67; strong diffuse nuclear positivity for p53 Chaichamnan et al., 2010 [13]
11 41, F 20% CD34 reactivity; positive for Ki-67; strong diffuse nuclear positivity for p53 Chaichamnan et al., 2010 [13]
12 65, F CD34 positivity in >70% of tumor cells; Ki-67 positivity in 20% of tumor cells; strong diffuse nuclear positivity for p53; positive for calretinin Gulati et al., 2011 [14]
13 52, F 40% CD34 reactivity; 20% Ki-67 reactivity; 80% p53 reactivity Alici et al., 2015 [15]
14 67, M Positive for Ki-67; positive for PHH3 Fieleke et al., 2015 [2]
15 42, M Positive for CD34 Liu et al., 2016 [16]
16 46, F Negative for CD34; negative for CK7; strongly positive for CK17; strong diffuse nuclear positivity for p53 CR