Table 1.

Source, MICs (mg/L), and resistance genes

Strain	Species WGS	Country	Isolate source	Aztreonam	Ceftazidime	Ciptrofloxacin	Colistin
16-551634	R. pickettii	The Netherlands	Blood culture	128	16	0.12	> 16
16-551636	R. pickettii	The Netherlands	Blood culture	256	8	0.12	> 16
16-543514	R. pickettii	The Netherlands	Blood culture	256	16	0.06	> 16
16-551632	R. pickettii	The Netherlands	Blood culture	256	8	0.12	> 16
16-551637	R. pickettii	The Netherlands	Blood culture	> 256	8	0.06	> 16
16-543504	R. pickettii	The Netherlands	Blood culture	> 256	32	0.12	> 16
16-551631	R. pickettii	The Netherlands	Furunkulosis	> 256	32	0.25	> 16
16-551635	R. pickettii	The Netherlands	Spondylodicitis	> 256	32	0.25	> 16
16-535633	R. mannitolilytica	Spain	CF	> 256	64	> 32	> 16
16-535634	R. mannitolilytica	Spain	CF	> 256	256	4	> 16
16-535635	R. mannitolilytica	Spain	CF	> 256	64	0.25	> 16
16-545260	R. mannitolilytica	USA	CF	> 256	32	> 32	> 16
16-545261	R. mannitolilytica	USA	CF	> 256	16	32	> 16
16-535632	R. mannitolilytica	Spain	CF	256	16	32	> 16
16-535638	R. mannitolilytica	Spain	CF	> 256	16	0.12	> 16
16-543498	R. mannitolilytica	The Netherlands	Blood culture	> 256	32	0.12	> 16
16-551633	R. insidiosa	The Netherlands	Blood culture	> 256	16	0.12	> 16
16-535637	R. new spp.	Spain	CF	> 256	16	0.12	> 16

Strain	Co-trimoxazole	Imipenem	Meropenem	Tobramycin	Resistance genes	Group1
16-551634	<=0.06	<=0.12	0.5	64	blaOXA-22 family, blaOXA-60 family	E2
16-551636	<=0.06	16	32	64	blaOXA-22 family, blaOXA-60 family	E2
16-543514	<=0.06	8	64	64	blaOXA-22 family, blaOXA-60 family	E2
16-551632	<=0.06	8	16	16	blaOXA-22 family, blaOXA-60 family	E2
16-551637	<=0.06	8	32	16	blaOXA-22 family, blaOXA-60 family	E2
16-543504	<=0.06	8	> 64	2	blaOXA-22 family, blaOXA-60 family	E1
16-551631	<=0.06	2	8	16	blaOXA-22 family, blaOXA-60 family	E1
16-551635	<=0.06	8	8	16	blaOXA-22 family, blaOXA-60 family	E1
16-535633	8	64	> 64	> 128	blaOXA-22 family, blaOXA-60 family	D2
16-535634	8	128	> 64	128	blaOXA-22 family, blaOXA-60 family	D2
16-535635	0.12	32	64	128	blaOXA-22 family, blaOXA-60 family	D2
16-545260	32	16	> 64	> 128	blaOXA-22 family, blaOXA-60 family, aadA2, ant(2'')-Ia, aph(6)-Id, cmlA1, strA, sul1	D2
16-545261	2	4	64	128	blaOXA-22 family, blaOXA-60 family, aadA2, ant(2'')-Ia, aph(6)-Id, cmlA1, strA, sul1	D2
16-535632	1	32	> 64	128	blaOXA-22 family, blaOXA-60 family	D2
16-535638	0.12	32	> 64	32	blaOXA-22 family, blaOXA-60 family	D1
16-543498	0.12	64	> 64	64	blaOXA-22 family, blaOXA-60 family	D1
16-551633	<=0.06	16	32	64	blaOXA-22 family, blaOXA-60 family	G
16-535637	0.25	8	8	32	blaOXA-22 family, blaOXA-60 family	F

¹Groups defined on basis of the ANIb (Fig. 2 and supplementary Fig. 1)