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. 2021 Sep 17;11:18535. doi: 10.1038/s41598-021-98089-3

Table 1.

Biographical, histological, surgical, and medical information for enrolled breast cancer patients.

Demographic and clinical information for breast cancer patients (n = 23)
Age, median (range) 70 (40–83)
Sex, n (%) 2 (8.70%) Male
21 (91.30%) Female
Cancer typea, n (%) 16 (69.57%) Ductal invasive
5 (21.74%) Lobular invasive
2 (8.70%) Invasive solid papillary carcinoma
1 (4.35%) Metastatic spindle cell carcinoma
Tumour grade, n (%) 16 (69.57%) Grade 2
7 (30.43%) Grade 3
Surgery type, n (%) 15 (65.22%) Mastectomy
8 (34.78%) Wide local excision
Tumour size in cm, median (range) 3 (0.2–10)
Largest metastatic focus in cm, median (range) 1.1 (0.1–3)
Antibiotic use within 1 month prior to surgeryb, n (%) 2 (8.70%)
Regular probiotic useb, n (%) 11 (47.83%)
History of breastfeedingb, n (%) 6 (26.09%)
History of adjuvant therapy, n (%) 0 (0%)
History of neoadjuvant therapy, n (%) 1 (4.35%)
Tumour necrosis, n (%) 9 (39.13%)
Calcifications—malignancy-associated, n (%) 8 (34.78%)
Calcifications—benign tissue-associated, n (%) 11 (47.83%)
Oestrogen receptor positive, n (%) 21 (91.30%)
Progesterone receptor positive, n (%) 18 (78.26%)
HER-2 receptor positive, n (%) 0 (0%)
Ductal ectasia, n (%) 3 (13.04%)
Focal lactational change, n (%) 1 (4.35%)
Lymphovascular invasion, n (%) 12 (52.17%)
Extranodal extension, n (%) 9 (39.13%)
Extensive intraductal component, n (%) 1 (4.35%)
Skin involvement, n (%) 8 (34.78%)

aSome patients had overlapping cancer types (e.g., both lobular carcinoma and ductal invasive carcinoma).

bOne patient did not provide information.