Fig. 3. Sunburst plot of the important KEGG pathways for predicting schizophrenia.

A neural network with layers based on KEGG pathway information was trained to predict schizophrenia. The relative importance was calculated for each pathway using the learned weights of this neural network. The sunburst plot is read from the center, which shows the output node with the prediction of the neural network. The inner ring represents the last layer with the highest-level pathways, followed by the mid-level pathways, and finally the lowest-level pathways. The gene and SNP layer are omitted for clarity.