Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 17;12(10):854. doi: 10.1038/s41419-021-04138-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a, b Western blot and bar graphs illustrating the SNARE proteins STX17, YKT6, VAMP8, SNAP29, and SNAP23 in α-Syn- and GFP-transduced neurons. α-Syn overexpression specifically leads to a decreased protein abundance of the SNAP25 family members SNAP23 and SNAP29, whereas the other SNARE proteins remain unchanged (n = 6/condition, n = 11 for SNAP29). c Bar graph showing similar levels of SNAP29 mRNA expression in α-Syn-transduced neurons as compared to GFP-transduced cells (n = 3/condition). For comparison of the means, a two-tailed unpaired t-test was used in b, c; ****P < 0.0001; Data are shown as means ± SEM.