Table 1.

Table depicting the bioenergetic and biophysical characteristics of the indicated complexes between SNAP29 and α-Syn.

	Complex_12b	Complex_38a	Complex_58a	Complex_79a	Complex_114d	Complex_68c
Interface area, Ų	986.5	1389	1243	1303	1310	1582
Solvation energy, kcal/mol	−7.633	−15.05	−18.92	−16.09	−16.55	−16.94
Total binding energy, kcal/mol	−12.6	−20.17	−21.88	−22.84	−21.88	−23.39
Hydrophobic P-value	0.6641	0.6599	0.4065	0.472	0.5421	0.6159
Number of hydrogen bonds	7	4	5	11	12	12
Number of salt bridges	5	9	2	5	0	3
Number of disulfide bonds	0	0	0	0	0	0

All complexes exhibit a low total binding energy, thus demonstrating an energetically favorable binding between SNAP29 and α-Syn.