Table 1.
Baseline characteristics of whole cohort.
| ACEi group (N = 33,358) | ARB group (N = 176,181) | SMD | Propensity-score matched population | SMD | ||
|---|---|---|---|---|---|---|
| ACEi group (N = 30,445) | ARB group (N = 30,445) | |||||
| Age group | ||||||
| 25–29 | 0.39 | 0.33 | 0.01 | 0.4 | 0.37 | 0 |
| 30–34 | 0.62 | 0.69 | − 0.01 | 0.66 | 0.62 | 0.01 |
| 35–39 | 1.12 | 1.35 | − 0.02 | 1.16 | 1.06 | 0.01 |
| 40–44 | 1.93 | 2.37 | − 0.03 | 1.98 | 1.75 | 0.02 |
| 45–49 | 3.4 | 3.63 | − 0.01 | 3.4 | 3.24 | 0.01 |
| 50–54 | 4.59 | 5.13 | − 0.03 | 4.58 | 4.49 | 0 |
| 55–59 | 5.75 | 6.07 | − 0.01 | 5.75 | 5.72 | 0 |
| 60–64 | 6.28 | 6.57 | − 0.01 | 6.23 | 6.52 | − 0.01 |
| 65–69 | 7.08 | 6.6 | 0.02 | 7.03 | 7.17 | − 0.01 |
| 70–74 | 6.68 | 6.59 | 0 | 6.71 | 6.91 | − 0.01 |
| 75–79 | 5.77 | 5.51 | 0.01 | 5.77 | 5.89 | − 0.01 |
| 80–84 | 3.69 | 3.21 | 0.03 | 3.7 | 3.69 | 0 |
| 85–89 | 1.73 | 1.26 | 0.04 | 1.66 | 1.67 | 0 |
| Female | 20.25 | 24.16 | − 0.09 | 21.01 | 21.21 | 0 |
| Medical history: general | ||||||
| Acute respiratory disease | 1.54 | 1.16 | 0.03 | 1.45 | 1.42 | 0 |
| Dementia | 0.88 | 1.31 | − 0.04 | 0.89 | 0.79 | 0.01 |
| Depressive disorder | 0.97 | 1.38 | − 0.04 | 1.01 | 0.98 | 0 |
| Diabetes mellitus | 10.88 | 10.31 | 0.02 | 10.9 | 10.96 | 0 |
| Gastroesophageal reflux disease | 1.57 | 1.76 | − 0.02 | 1.57 | 1.51 | 0 |
| Gastrointestinal hemorrhage | 0.95 | 0.7 | 0.03 | 0.89 | 0.87 | 0 |
| Hyperlipidemia | 7.61 | 8.32 | − 0.03 | 7.73 | 7.23 | 0.02 |
| Lesion of liver | 1.42 | 1.32 | 0.01 | 1.4 | 1.28 | 0.01 |
| Obesity | 0.11 | 0.31 | − 0.04 | 0.11 | 0.12 | 0 |
| Osteoarthritis | 0.56 | 0.88 | − 0.04 | 0.6 | 0.54 | 0.01 |
| Pneumonia | 2.32 | 1.64 | 0.05 | 2.22 | 2.29 | 0 |
| Renal impairment | 2.84 | 3.43 | − 0.03 | 2.91 | 2.83 | 0 |
| Urinary tract infectious disease | 0.81 | 0.66 | 0.02 | 0.8 | 0.8 | 0 |
| Visual system disorder | 4.22 | 4.65 | − 0.02 | 4.25 | 4.25 | 0 |
| Medical history: Cardiovascular disease | ||||||
| Atrial fibrillation | 2.18 | 1.57 | 0.04 | 2.28 | 2.41 | − 0.01 |
| Coronary arteriosclerosis | 3.88 | 1.79 | 0.13 | 3.81 | 3.92 | − 0.01 |
| Heart disease | 29.56 | 13.85 | 0.39 | 27.91 | 28.88 | − 0.02 |
| Heart failure | 7 | 2.36 | 0.22 | 6.34 | 6.48 | − 0.01 |
| Ischemic heart disease | 19.56 | 6.51 | 0.4 | 17.88 | 18.34 | − 0.01 |
| Peripheral vascular disease | 2.81 | 3.29 | − 0.03 | 2.81 | 2.79 | 0 |
| Medical history: Neoplasms | ||||||
| Malignant neoplasm of anorectum | 0.27 | 0.23 | 0.01 | 0.26 | 0.22 | 0.01 |
| Malignant neoplastic disease | 3.77 | 4.04 | − 0.01 | 3.57 | 3.39 | 0.01 |
| Malignant tumor of breast | 0.27 | 0.3 | − 0.01 | 0.27 | 0.24 | 0.01 |
| Primary malignant neoplasm of prostate | 0.27 | 0.25 | 0 | 0.26 | 0.28 | 0 |
Data are presented as %.
ACEi Angiotensin converting enzyme inhibitoir, ARB Angiotensin receptor blocker, SMD standardized mean difference.
Current table showed the aggregated balance before and after matching only for limited covariates from 7 databases.