Table 3.
Multivariable linear regression analysis to evaluate independent associations between log-transformed total FGF2 3 (independent variable) and hemoglobin SDS (dependent variable). VIF: variance inflation factor; FGF23: fibroblast growth factor 23; eGFR: estimated glomerular filtration rate; EPO: erythropoietin; ERFE: erythroferrone
Model | Independent variables | Coefficient | p-value | VIF | R 2 |
---|---|---|---|---|---|
1 | Log Total FGF23 | −3.496 | <0.001 | 1.37 | 0.40 |
eGFR | 0.016 | 0.07 | 1.37 | ||
2 | Log Total FGF23 | −4.354 | <0.001 | 1.02 | 0.40 |
Iron | −0.004 | 0.52 | 1.06 | ||
Ferritin | −0.001 | 0.50 | 1.34 | ||
Hepcidin | −0.002 | 0.77 | 1.26 | ||
3 | Log Total FGF23 | −2.930 | 0.001 | 1.06 | 0.42 |
Log EPO | −1.924 | 0.006 | 1.61 | ||
Log ERFE | −0.199 | 0.61 | 1.55 | ||
4 | Log Total FGF23 | −3.152 | <0.001 | 1.45 | 0.45 |
Phosphate SDS | −0.104 | 0.48 | 1.06 | ||
Calcium | 0.945 | 0.021 | 1.52 | ||
5 | Log Total FGF23 | −4.303 | <0.001 | 1.11 | 0.38 |
TNF-α | −0.020 | 0.40 | 1.48 | ||
IL-8 | 0.008 | 0.24 | 1.39 | ||
6 | Log Total FGF23 | −3.301 | <0.001 | 1.07 | 0.30 |
Mycophenolate Dose | −0.002 | 0.06 | 1.07 |