Figure 1. Immunologic mechanisms and potential of HER2 targeted mAb therapies.

A) Diagram illustrating the potential MOAs involved in anti-tumor mAb directed therapies. B) A PET scan demonstrating FDG avid sites of disease in a patient initially diagnosed with metastatic HER2 positive breast cancer who had a complete response, or C) following induction docetaxel combined with trastuzumab and pertuzumab.