Figure 5.
HRP2 and MPP8 colocalize at the E-cadherin locus. (a) The HUSH complex coimmunoprecipitates with HRP2 in MDA-MB-231 cells. (b) ChIP-qPCR analysis of MPP8, HRP2, and H3K9me3 at E-cadherin in MDA-MB-231 cells demonstrating enrichment of both MPP8 and HRP2 at similar levels. TSS indicates the position (in bp) from the transcriptional start site. Statistical significance was calculated using a paired t test (n = 6; *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001).
