Table 3.
QST measures associated with hyperalgesia intensity
| Dependent Measure | Factor | F_value | p | Factor | F_value | p | |
|---|---|---|---|---|---|---|---|
| STMP 64 mN △ | WDT | 2.618 | 0.111 | WDT:time | 1.465 | 0.235 | |
| STMP 128 mN △ | WDT | 1.248 | 0.269 | WDT:time | 0.054 | 0.947 | |
| STMP 256 mN △ | WDT | 1.598 | 0.211 | WDT:time | 0.331 | 0.719 | |
| STMP 512 mN △ | WDT | 0.116 | 0.734 | WDT:time | 0.714 | 0.492 | |
| STMP 64 mN △ | HPT | 10.434 | 0.002 ** | HPT:time | 1.782 | 0.173 | |
| STMP 128 mN △ | HPT | 1.677 | 0.201 | HPT:time | 0.937 | 0.395 | |
| STMP 256 mN △ | HPT | 1.040 | 0.312 | HPT:time | 0.482 | 0.619 | |
| STMP 512 mN △ | HPT | 0.000 | 0.998 | HPT:time | 0.195 | 0.823 | |
| STMP 64 mN △ | STMP64 | 7.435 | 0.008 ** | STMP64:time | 1.369 | 0.258 | |
| STMP 64 mN △ | STMP128 | 23.734 | <0.001 ** | STMP128:time | 4.867 | 0.009 ** | |
| interaction | estimate | t | p | ||||
| STMP128*time_t1-t2 | −0.242 | −2.338 | 0.021* | ||||
| STMP128*time_t1-t3 | −0.307 | −2.958 | 0.004 ** | ||||
| STMP128*time_t2-t3 | −0.064 | −0.620 | 0.536 | ||||
| STMP 64 mN △ | STMP256 | 10.187 | 0.002 ** | STMP256:time | 7.175 | 0.001 ** | |
| interaction | estimate | t | P | ||||
| STMP256*time_t1-t2 | −0.115 | −1.767 | 0.08 | ||||
| STMP256*time_t1-t3 | −0.247 | −3.785 | <0.001 ** | ||||
| STMP256*time_t2-t3 | −0.132 | −2.018 | 0.046* | ||||
| STMP 64 mN △ | STMP512 | 23.927 | <0.001 ** | STMP512:time | 6.947 | 0.001 ** | |
| interaction | estimate | t | P | ||||
| STMP512*time_t1-t2 | −0.069 | −1.405 | 0.163 | ||||
| STMP512*time_t1-t3 | −0.182 | −3.692 | <0.001 ** | ||||
| STMP512*time_t2-t3 | −0.113 | −2.287 | 0.024* | ||||
| STMP 128 mN △ | STMP64 | 5.993 | 0.017* | STMP64:time | 4.333 | 0.015* | |
| interaction | estimate | t | p | ||||
| STMP64*time_t1-t2 | −0.730 | −2.178 | 0.031* | ||||
| STMP64*time_t1-t3 | 0.210 | 0.626 | 0.532 | ||||
| STMP64*time_t2-t3 | 0.939 | 2.804 | 0.006 ** | ||||
| STMP 128 mN △ | STMP128 | 0.025 | 0.874 | STMP128:time | 1.096 | 0.338 | |
| STMP 128 mN △ | STMP256 | 0.454 | 0.503 | STMP256:time | 0.879 | 0.418 | |
| STMP 128 mN △ | STMP512 | 1.848 | 0.179 | STMP512:time | 0.862 | 0.425 | |
| STMP 256 mN △ | STMP64 | 0.431 | 0.514 | STMP64:time | 1.986 | 0.142 | |
| STMP 256 mN △ | STMP128 | 0.088 | 0.768 | STMP128:time | 0.203 | 0.817 | |
| STMP 256 mN △ | STMP256 | 1.219 | 0.274 | STMP256:time | 0.443 | 0.643 | |
| STMP 256 mN △ | STMP512 | 0.089 | 0.767 | STMP512:time | 0.181 | 0.834 | |
| STMP 512 mN △ | STMP64 | 0.343 | 0.56 | STMP64:time | 4.915 | 0.009 ** | |
| interaction | estimate | t | p | ||||
| STMP64*time_t1-t2 | −0.496 | −1.560 | 0.122 | ||||
| STMP64*time_t1-t3 | 0.501 | 1.576 | 0.118 | ||||
| STMP64*time_t2-t3 | 0.997 | 3.135 | 0.002 ** | ||||
| STMP 512 mN △ | STMP128 | 0.320 | 0.574 | STMP128:time | 0.913 | 0.404 | |
| STMP 512 mN △ | STMP256 | 0.635 | 0.429 | STMP256:time | 2.517 | 0.085 | |
| STMP 512 mN △ | STMP512 | 0.906 | 0.345 | STMP512:time | 0.469 | 0.627 |
STMP: Suprathreshold mechanical pain. STMP△ [(post-capsaicin)-t0] = STMP t(post-capsaicin)-STMP t0. Post-capsaicin values calculated for 3 time points: t1-t0, t2-t0, and t3-t0. WDT: Warmth detection threshold. HPT: Heat pain threshold.
*
Significant at p<0.05.
**
Significant at q<0.05. Values highlighted in bold are significant after AFDR correction.