Table 2:
Outcomes abstracted from included studies.
Author | Groups | R0 resection% | T downstaging% | pCR% | OS% | DFS/DRTF% | |
---|---|---|---|---|---|---|---|
Washington Cohort | Markovina et al. (2017) | Study | NR | 75 | 28 | 96 (3-year) | 80 (3-year) |
Control | NR | 41 | 16 | 88 (3-year) | 70 (3-year) | ||
Myerson et al. (2014) | Study | NR | 71 | 28 | NR | NR | |
Control | |||||||
Polish Cohort | Ciseł et al. (2019) | Study | 77 | NR | 16 | 49 (8-year) | 43 (8-year) |
Control | 71 | NR | 12 | 49 (8-year) | 41 (8-year) | ||
Bujko et al. (2016) | Study | 77 | NR | 16 | 73 (3-year) | 53 (3-year) | |
Control | 71 | NR | 12 | 65 (3-year) | 52 (3-year) | ||
Bujko et al. (2013) | Study | 73 | 71 | 21 | NR | NR | |
Control | 71 | 73 | 8 | NR | NR | ||
Iranian Cohort | Aghili et al. (2020) | Study | 100 | 54.8 | 32.2 | NR | NR |
Control | 96.2 | 53.8 | 23.1 | NR | NR | ||
Aghili et al. (2018) | Study | NR | NR | 30.8 | 65 (3-year) | 55 (3-year) | |
Control | |||||||
Baltimore Cohort | Jia et al. (2019) | Study | 69.2 | NR | 35 | NR | NR |
Control | |||||||
Danish Cohort | Van Dijk et al. (2013) | Study | 72 | 47 | 26 | 80 (2-year) | NR |
Control | |||||||
RAPIDO trial | Bahadoer et al. (2020) | Study | 90 | NR | 28 | 89.1 (3-year) | 23.7 (3-year DRTF) |
Control | 90 | NR | 14 | 88.8 (3-year) | 30.4 (3-year DRTF) | ||
Indian Cohort | Thakur et al. (2020) | Study | 92.8 | NR | 0.071 | NR | NR |
Control | 92.3 | NR | 0 | NR | NR |
(pCR = pathological complete response; OS = overall survival; DFS = disease free survival, DRTF = disease-related treatment failure, NR = not reported)