Table 1.

Summary of clinical cases reporting the use of ascorbate in G6PD^def.

Hemolytic Trigger	Dose	Treatment	Dose	Response to Trigger						Type of Study	References
Ascorbate	80g/day, IV	Blood transfusion		X	X		X	X	X	case study	[118]
Ascorbate	40g/3x/week, IV + 20-40g/daily/oral			X	X		X			case study	[119]
	Increased to 80g/3x/week, IV
Ascorbate	30g/day, IV	Blood transfusion	8 days	X					X	case study	[120]
	60g/day, IV
Fava Beans Ascorbate	~10 beans							X		case study	[121]
	250-500mg/day, oral
Ascorbate	4-6g/6hr, oral	Blood transfusion			X		X			case study	[122]
Ascorbate	30g/day, IV	Blood transfusion		X	X	X	X			case study	[123]
Ascorbate	75g/day, IV	Blood transfusion		X	X	X	X			case study	[124]
Ascorbate	2g/day, IV	-			X		X			case study	[125]
Rasburicase	6mg	Ascorbate	5g/6hrs, IV	X		X	X			case study	[46]
		Blood transfusion
Rasburicase	6mg	Ascorbate	1g/day, oral	X	X	X				case study	[47]
		Blood transfusion
Chloroquine + Covid-19	600mg/day	Ascorbate	1g/4x/day	X		X				case study	[23]
		Blood transfusion
Fava Beans Ciprofloxacin Acetaminophen	500mg/2x/daily 1000mg/3x/daily	Ascorbate	1g/4x/day	X	X	X	X			case study	[48]
		Blood transfusion
				Hemolysis/Anemia	Dark Urine	Methemoglobinemia	Respiratory Distress /↓O2	Death	Renal Failure