Table 2.
Factors Associated With Proportion of Days That Patients Experienced Deliriuma
| Variable | Unadjusted |
Adjusted |
||||
|---|---|---|---|---|---|---|
| Difference | 95% CI | P Value | Difference | 95% CI | P Value | |
| Intervention vs preintervention | –5.3% | –9.8 to –0.7 | .02 | –4.9% | –9.2% to –0.5% | .03 |
| Age per y | 0.1% | 0.0% to 0.3% | .06 | 0.1% | 0.0% to 0.3% | .07 |
| Female vs male sex | 3.1% | –1.6% to 8.2% | .21 | 3.5% | –1.1% to 8.4% | .16 |
| Other vs White race | 7.6% | 0.7% to 14.5% | .03 | 8.4% | 2.2% to 15.7% | .01 |
| Charlson Comorbidity Index, per point | 0.4% | –0.4% to 1.3% | .40 | 0.6% | –0.2% to 1.6% | .16 |
| Home sleep medication, yes vs no | –1.1% | –6.2% to 5.0% | .71 | –1.5% | –6.7% to 3.9% | .58 |
| SICU vs CVICU | 5.6% | 0.9% to 10.5% | .02 | 5.8% | –7.9% to 16.2% | .30 |
| Admission category, vs general or trauma surgery | ||||||
| Cardiology | –9.7% | –14.9% to –3.5% | < .001 | –3.6% | –16.6% to 4.2% | .24 |
| Cardiothoracic surgery | –1.7% | –7.0% to 3.6% | .52 | 0.2% | –13.4% to 10.6% | .97 |
| Coma at first ICU assessment vs none | 21.1% | 14.3% to 28.6% | < .001 | 21.4% | 14.4% to 29.3% | < .001 |
CCI = Charlson Comorbidity Index; CVICU = cardiovascular ICU; SICU = surgical ICU.
Values represent proportion of days with a positive delirium assessment during an admission among the first 14 d of the ICU stay that delirium was assessed. P values calculated using linear regression with generalized estimating equations under an independence correlation structure and with robust Huber-White sandwich SEs to account for variance across patients (heteroscedasticity). 95% CIs estimated using the bias-corrected and accelerated bootstrap method with 2,000 samples. Delirium proportion data missing for 7 (2%) and 8 (2%) preintervention and intervention patients, respectively.