TABLE 2.
Clinical evaluation of CWP1 as a diagnostic marker with the Alexon testa
| Alexon test parameter | Result for:
|
||
|---|---|---|---|
| Study 1 (Sacred Heart Medical Center, Spokane, Wash.) | Study 2 (Dekalb Medical Center, Decatur, Ga.) | Study 3 (VRL, San Antonio, Tex.) | |
| Total no. of stools | 114 | 221 | 200 |
| Total no. positive | 34 | 46 | 16 |
| Total no. negative | 75 | 165 | 177 |
| Total no. of discrepancies | 5 | 10 | 7 |
| % Sensitivity | 100.0 | 100.0 | 100.0 |
| % Specificity | 94.9 | 94.3 | 96.2 |
| Positive predictive value (%) | 89.7 | 82.1 | 69.5 |
| Negative predictive value (%) | 100.0 | 100.0 | 100.0 |
| % Correlation | 96.5 | 95.5 | 96.5 |
a
The ELISA was performed as instructed by the manufacturer. O&P was done by in-house methods implemented at each study site. All stool specimens were preserved in 10% buffered formalin.