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. 2021 Apr 8;160(3):1026–1034. doi: 10.1016/j.chest.2021.03.056

Table 2.

Association of TyG With Study Outcomes, With Concurrent Adjustment for Insulin Resistance (HOMA-IR) or the Metabolic Syndrome

Variable TyG With Concurrent Adjustment for
log(HOMA-IR) Metabolic Syndrome
Symptom, aOR (95% CI)
 Cough 1.24 (1.02 to 1.51) 1.22 (1.01 to 1.47)
 Phlegm production 1.19 (0.98 to 1.44) 1.17 (0.97 to 1.42)
 Wheeze 1.21 (1.04 to 1.41) 1.13 (0.98 to 1.31)
 Exertional dyspnea 1.17 (1.02 to 1.35) 1.14 (0.99 to 1.32)
Condition, aOR (95% CI)
 Asthma 1.10 (0.92 to 1.31) 1.05 (0.88 to 1.26)
 Chronic bronchitis 1.19 (0.98 to 1.44) 1.19 (0.98 to 1.46)
 Emphysema 1.00 (0.65 to 1.54) 0.98 (0.63 to 1.52)
Spirometry, aMD (95% CI)
 FEV1pp –0.76 (–2.26 to 0.73) –0.68 (–2.41 to 1.04)
 FVCpp –1.24 (–2.76 to 0.28) –1.56 (–2.99 to –0.13)
 FEV1/FVC 0.32 (–0.27 to 0.90) 0.67 (0.01 to 1.33)
Spirometry pattern, aRRR (95% CI)
 Obstructive 0.87 (0.70 to 1.08) 0.83 (0.66 to 1.06)
 Restrictive 1.37 (0.98 to 1.92) 1.33 (1.02 to 1.74)

aMD = adjusted mean difference; aOR = adjusted OR; aRRR = adjusted relative risk ratio; FEV1pp = percent-predicted FEV1; FVCpp = percent-predicted FVC; HOMA-IR = homeostatic model assessment of insulin resistance; TyG = triglyceride-glucose index.

Adjusted for age, sex, race/ethnicity, BMI, poverty-income ratio, cardiovascular disease, smoking status, smoking years, and fasting time.