Skip to main content
. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Pain. 2021 Oct 1;162(10):2548–2557. doi: 10.1097/j.pain.0000000000002243

Table 2.

BMS disease description

2A. ICD-11 BMS disease description. 2B. Revisions to ICD-11 BMS disease description that met consensus in the Delphi study. 2C. ICD-11 BMS disease description with merged revisions that met consensus in the Delphi study.
Chronic burning mouth pain is chronic orofacial pain with an intraoral burning or dysesthetic sensation that recurs for more than two hours per day on 50 % of the days over more than three months, without evident causative lesions on clinical investigation and examination. It is characterized by significant emotional distress (anxiety, anger/frustration or depressed mood) or interference with orofacial functions such as eating, yawning, speaking etc. Chronic burning mouth pain is multifactorial: biological, psychological and social factors contribute to the pain condition. The diagnosis is appropriate independently of identified biological or psychological contributors unless another diagnosis would better account for the presenting symptoms. Other chronic headache or orofacial pain diagnoses to be considered are listed under chronic secondary headache and orofacial pain. • Use term “burning mouth disorder” instead of “burning mouth syndrome” and “chronic burning mouth pain.”
• Add expanded description of intraoral location affected including:
 ○ “Multiple intraoral sites may be affected”
 ○ “The most common site affected is the tongue”
 ○ “Symptoms are often bilateral”
• Remove that symptoms recur “for more than two hours per day”
• Revised “causative lesions” to “causes”
• Added “laboratory findings” to clinical investigation/examination.
• Added “associated symptoms may include dysgeusia and/or xerostomia (subjective dry mouth).”
• Revised “It is characterized by significant emotional distress […]” to “It can be associated with emotional distress […]”
• Removed “yawning” from orofacial functions affected by BMS.
• Added “with neuropathic characteristics” to statement “[…] biological, psychological and social factors contribute to the pain condition.”
• Added as footnote “the following local and systemic causes of oral burning should be evaluated: oral mucosal disease, parafunctional habit of the tongue, hyposalivation, oral candidiasis, anemia, B12 and B9 deficiency, diabetes mellitus, Angiotensin Converting Enzyme (ACE) inhibitor medication. When one of these conditions is found it should be treated and its contribution to oral burning symptoms should be made before a diagnosis of Burning Mouth Disorder is considered.
Burning mouth disorder is chronic orofacial pain with an intraoral1,2,3 burning or dysaesthetic sensation that recurs on 50 % of the days over more than three months, without evident causes4 on clinical investigation/ examination and laboratory findings. Associated symptoms may include dysgeusia and/or xerostomia (subjective dry mouth). It may be associated with emotional distress (anxiety, anger/frustration or depressed mood) or interference with orofacial functions such as eating, speaking etc. Burning mouth disorder is multifactorial: biological, psychological and social factors contribute to the pain condition with neuropathic characteristics. The diagnosis is appropriate independently of identified biological or psychological contributors unless another diagnosis would better account for the presenting symptoms. Other chronic headache or orofacial pain diagnoses to be considered are listed under chronic secondary headache and orofacial pain.
1Multiple intraoral sites may be affected.
2The most common site affected is the tongue.
3Symptoms are often bilateral.
4The following local and systemic causes of oral burning should be evaluated: oral mucosal disease, parafunctional habit of the tongue, hyposalivation, oral candidiasis, anemia, vitamin B12 and B9 deficiency, diabetes mellitus, Angiotensin Converting Enzyme (ACE) inhibitor medication. When present, these other conditions should be treated and their contribution to oral burning symptoms should be evaluated before a diagnosis of Burning Mouth Disorder is considered.