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Box-Behnken design variables for preparing Farnesol loaded niosomes.
| Factor | Level used (actual coded) |
|||
|---|---|---|---|---|
| Low (-1) | Medium (0) | High (1) | ||
| Independent variables | ||||
| A | Cholesterol: Span 20 (ratio) | 0.75:0.5 | 01:01 | 1.25:1.5 |
| B | Farnesol (mg) | 0.25 | 0.375 | 0.5 |
| C |
Homogenization speed (rpm) |
7000 |
8500 |
10000 |
| Dependent variables | ||||
| A | Particle size(nm) | |||
| B | % Entrapment efficiency | |||
| (Farnesol) | ||||
