Table 3.

A) The scoring system for skin reactions (skin irritation test); B) The Score of Primary Irritation (SPI) index.

(A) The scoring system for skin reactions (skin irritation test)
Reaction	Score
Erythema
No erythema	0
Very slight erythema (barely perceptible)	1
Well-defined erythema	2
Moderate to severe erythema	3
Severe erythema (beet redness) to eschar formation	4
Edema
No edema	0
Very slight edema (barely perceptible)	1
Well-defined edema (edges of the area well defined by definite raising)	2
Moderate edema (raising approximately 1 mm)	3
Severe edema (raised more than 1 mm and extending beyond the area of exposure)	4
Total possible score for primary irritation	8
(B) The Score of Primary Irritation (SPI) index
Category	Primary Irritation Index (PII)
Negligible	0–0.4
Slight irritation	0.5–1.9
Moderate irritation	2–4.9
Severe irritation	5–8