Figure 2.

RGO-SMEDDS suppresses xenograft liver tumor growth in vivo

(A) Representative images of xenograft tumor status assessed by in vivo fluorescence imaging (upper) or viewing with naked eye (lower). (B and C) Tumor weight by the time of resection and tumor volume growth curve in nude mice. Tumor volume was calculated from tumor length and width, measured every 2 days. (D) Representative pictures of the xenograft tumors before and after resection in comparison between RGO and the control group. (E and F) Growth curve and weight of xenograft tumors in C57BL/6 mice. Tumor volume was calculated from tumor length and width, measured every 2 days. (G) H&E staining and immunohistochemistry (IHC) staining of Ki67 of xenograft tumor tissues from nude mice and C57BL/6 mice. Scale bars, 60 μm. The data are shown as the mean ± SD. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.