Table 2.
Summary of EEG, MRI and lab/biopsy results of patients included in the study.
| Patient # | EEG | MRI | Lab/biopsy results |
|---|---|---|---|
| 1 | Burst suppression pattern | Intraventricular hemorrhage, subdural hematomas, ventriculomegaly. delayed myelination, bi-thalamic lesions, abnormal signal intensity/restricted diffusion at myelinated areas including the posterior limb of the internal capsule | Elevated plasma and CSF glycine |
| 2 | Encephalopathic pattern, generalized spike-wave complexes | Normal | Lafora bodies in axillary skin biopsy |
| 3 | Encephalopathic pattern | Cerebral atrophy | - |
| 4 | Poor organization, generalized sharp/wave complexes and slow sharp delta waves of high voltage, hypsarrhythmia | Delay of myelination, decrease in cerebral volume | - |
| 5 | Hypsarrhythmia | Corpus callosum dysgenesis, colpocephaly with dilatation of the occipital horns bilaterally | Lactic acidosis |
| 6 | Generalized sharp wave complexes | Unrevealing | - |
| 7 | Compatible with generalized epilepsy | Generalized atrophy, especially at frontal lobes | - |
| 8 | Interictal epileptic activity on left dorsal frontocentral region, midline | Abnormal periventricular and occipital white matter, old infarct of the left basal ganglia | - |
| 9 | Generalized sharp wave complexes | Hypoplasia of posterior part of corpus callosum. | - |
| 10 | Burst suppression pattern, hypsarrhythmia, bilateral occipital slow waves, focal epileptic discharges | Normal | - |
Abbreviations: mo.: months, y.: years, MRI: Magnetic resonance Imaging, EEG: Electroencephalogram, CSF: cerebrospinal fluid.