Table 1.
ID | Sex | Target | Vector | MRI | [11C]DCZ | [18F]FDG | Behavior | Histology |
---|---|---|---|---|---|---|---|---|
Marmo1 | Male | Left SN | AAV2.1-hSyn1-hM3Dq-IRES-AcGFP | + | + | + | + | |
Marmo2 | Male | Right SN | AAV2.1-hSyn1-hM3Dq-IRES-AcGFP | + | + | + | + | |
Marmo3 | Female | Left SN | AAV2-CMV-hM3Dq, AAV2-CMV-AcGFP | + | + | + | + | |
Marmo4 | Female | Left SN | AAV2.1-TH-FLAG-hM3Dq | + | + | + | + | + |
SN, substantia nigra; MRI, magnetic resonance imaging; [11C]DCZ, [11C]deschloroclozapine; [18F]FDG, [18F]fluorodeoxyglucose; AcGFP, Aequorea coerulescens green fluorescent protein.