Table 1.
Summary of subject information and experiments
| ID | Sex | Target | Vector | MRI | [11C]DCZ | [18F]FDG | Behavior | Histology |
|---|---|---|---|---|---|---|---|---|
| Marmo1 | Male | Left SN | AAV2.1-hSyn1-hM3Dq-IRES-AcGFP | + | + | + | + | |
| Marmo2 | Male | Right SN | AAV2.1-hSyn1-hM3Dq-IRES-AcGFP | + | + | + | + | |
| Marmo3 | Female | Left SN | AAV2-CMV-hM3Dq, AAV2-CMV-AcGFP | + | + | + | + | |
| Marmo4 | Female | Left SN | AAV2.1-TH-FLAG-hM3Dq | + | + | + | + | + |
SN, substantia nigra; MRI, magnetic resonance imaging; [11C]DCZ, [11C]deschloroclozapine; [18F]FDG, [18F]fluorodeoxyglucose; AcGFP, Aequorea coerulescens green fluorescent protein.