Figure 5.

LPS-activated lymph node (LN) cells are lymphocytes composed of similar proportions of B and T cells. (A) Expression of CD3 and CD19, markers of B and T cells, in CD69+ single live cells from the mesenteric (top row) and inguinal lymph nodes (bottom row) that were harvested from mice treated with IFNγ and saline (control, left column), IFNγ- and LPS-treated wild-type littermates (wild-type [WT] + LPS, middle column), and IFNγ- and LPS-treated glial^MHC2KO mice (WT + knockout [KO], left column). (B) Percentage of CD69+ single live cells expressing either B-cell marker CD19 or T-cell marker CD3 in the mesenteric (left) and inguinal (right) lymph nodes of glial^MHC2KO animals (KO) and wild-type littermates (WT) before (controls) and after LPS stimulation (n = 4–7 mice).