| REAGENT or RESOURCE | SOURCE | IDENTIFIER | 
|---|---|---|
| Antibodies | ||
| Rabbit monoclonal anti-Vimentin (1:100) | Proteintech | Cat#10366-1-AP; RRID: AB_2273020 | 
| Rabbit monoclonal anti-IGFBP1 (1:1000) | Cell Signaling Technology | Cat#31025; RRID: AB_2798998 | 
| Rabbit Polyclonal anti-PRL (1:1000) | Affinity Biosciences | Cat#DF6506; RRID: AB_2838468 | 
| Rabbit Polyclonal anti-TET3 (1:1000) | Merck Millipore | Cat#ABS463 | 
| Rabbit Polyclonal anti-Col1A1 (1:1000) | Abcam | Cat#ab34710; RRID: AB_731684 | 
| Rabbit Polyclonal anti-GAPDH (1:3000) | Abcam | Cat#ab9485; RRID: AB_307275 | 
| HRP-conjugated secondary antibody (1:5000) | Abcam | Cat#ab6721; RRID: AB_955447 | 
| Cy3-tagged secondary antibody (1:500) | Boster | Cat#BA1032; RRID: AB_2716305 | 
| Rabbit monoclonal anti-5hmC | Abcam | Cat#ab214728; RRID: AB_2797407 | 
| Rabbit Polyclonal anti-TET3 (ChIP) | Sigma-Aldrich | Cat#ABE290 | 
| Bacterial and virus strains | ||
| BJ5183 | Unibio | Cat#ST1039 | 
| XL1-Blue | Unibio | Cat#ST1054 | 
| Biological samples | ||
| Human endometrial tissues of proliferative-phase women and secretory-phase women | Department of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University | N/A | 
| Human decidual tissues of EPL patients and normal early pregnancy women | Department of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University | N/A | 
| Chemicals, peptides, and recombinant proteins | ||
| TRIzol | Invitrogen | Cat#15596-026 | 
| DMEM/F12 | Procell | Cat#PM150312 | 
| Fetal bovine serum (FBS) | Procell | Cat#164210-500 | 
| Trypsin | Procell | Cat#PB180225 | 
| Penicillin-Streptomycin Solution | Procell | Cat#PB180120 | 
| PBS | Procell | Cat#PB180327 | 
| Collagenase I | Sigma | Cat#C0130-100MG | 
| TritonX-100 | Beyotime | Cat#ST795 | 
| PFA | Beyotime | Cat#P0099 | 
| Lipofectamine 3000 | Thermo Fisher Scientific | Cat#L3000-015 | 
| RIPA lysis buffer | Beyotime | Cat#P0013K | 
| PMSF | Beyotime | Cat#ST505 | 
| DAPI | Beyotime | Cat#C1002 | 
| Oestradiol | Targetmol | Cat#T1048 | 
| Progesterone | Targetmol | Cat#T5040 | 
| cAMP | Targetmol | Cat#TC02745 | 
| DL2000 DNA Marker | TIANGEN | Cat#MD114-02 | 
| Critical commercial assays | ||
| SYBR Green PCR kit | VAZYME | Cat#Q111-02 | 
| Plasmid Midi kit | Qiagen | Cat#12143 | 
| CCK-8 assay kit | Beyotime | Cat#C0037 | 
| BCA Protein Assay Kit | Beyotime | Cat#P0010S | 
| Dual Luciferase Reporter Kit | Beyotime | Cat#RG027 | 
| hMeDIP Kit | Abcam | Cat#ab117134 | 
| Experimental models: Organisms/strains | ||
| Mouse: C57BL/6 | Vital River Animal Center, Beijing, China | Cat#213 | 
| Oligonucleotides | ||
| Primers for miR-29a-3p: 5’-TGCGCTAGCACCATCTGAAATC-3’ and 5’-CCAGTGCAGGGTC CGAGGTATT-3’ | This paper | N/A | 
| Primers for U6: 5’-CGCTTCGGCAGCACATATAC-3’ and 5’-AAATATGGAA CGCTTCACGA-3’ | This paper | N/A | 
| Primers for TET1: 5’-CCTGCTCACGGCTCGGTTTTGATTG-3’ and 5’-G GGAGAGGCGGGTTGGATGATTACG-3’ | This paper | N/A | 
| Primers for TET2: 5’-CCATTCCTGATACCATCAC CTCCCA-3’ and 5’-GGCTTACCCCGAAGTTACGTCTTTC-3’ | This paper | N/A | 
| Primers for TET3: 5’-CCAAC GAGGAAATAGCGATTGACTG-3’ and 5’-CCCATTGTAGAGGTTATGCTGGTCC -3’ | This paper | N/A | 
| Primers for Col1A1: 5’-GTTCCTCCCTGCTCTCCATC-3’ and 5’-GAGGTCCACAAAG CTGAACA-3’ | This paper | N/A | 
| Primers for GAPDH: 5’-TCAAGAAGGTGGTGAAGCAGG-3’ and 5’-TCAA AGGTGGAGGAGTGGGT-3’ | This paper | N/A | 
| MiR-29a agomir and antagomir | GenePharma | N/A | 
| Control agomir and antagomir | GenePharma | N/A | 
| Recombinant DNA | ||
| pAd5 vector | Addgene | Cat#122555 | 
| pGL3 reporter vector | promega | Cat#E1751 | 
| pRL-TK reporter | promega | Cat#E2241 | 
| Software and algorithms | ||
| SPSS 17.0 software | SPSS Inc. | N/A |