Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 10;15:100392. doi: 10.1016/j.ynstr.2021.100392

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Published by Elsevier Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 5 — Validation and replication of differential gene expression.

Validation was performed on the top 10 DEGs, ranked by p-value. The expression patterns of Ppp3ca, Grm4, Grm3, Inhba, Gpx6, Pcdh8, Txnrd1, and Ngf (the 1st through 7th and 9th ranked DEGs) were consistent with array data. The expression patterns of Nqo1 and Txnrd3 (the 8th and 10th ranked DEGs) failed to validate findings from the array, though the trends were similar. Replication attempted using amygdala tissue from a separate set of mice revealed similar patterns of gene expression except for Txnrd1, where no significant differences or trends were found. Graphs indicate mean ± standard error of the mean. *p < 0.05, **<0.01, ***<0.001.

Fig. 5 — Validation and replication of differential gene expression.

Validation was performed on the top 10 DEGs, ranked by p-value. The expression patterns of Ppp3ca, Grm4, Grm3, Inhba, Gpx6, Pcdh8, Txnrd1, and Ngf (the 1st through 7th and 9th ranked DEGs) were consistent with array data. The expression patterns of Nqo1 and Txnrd3 (the 8th and 10th ranked DEGs) failed to validate findings from the array, though the trends were similar. Replication attempted using amygdala tissue from a separate set of mice revealed similar patterns of gene expression except for Txnrd1, where no significant differences or trends were found. Graphs indicate mean ± standard error of the mean. *p < 0.05, **<0.01, ***<0.001.