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. 2021 Aug 31;118(37):e2105279118. doi: 10.1073/pnas.2105279118

Fig. 4.

Fig. 4.

Virus exposure (violet, low; green, high) for the four ambient conditions simulated: T=5 °C and RH=50to90% (A and B) and T=20 °C and RH=50to90% (C and D). Exposure is defined as the number of virus copies (virions) that go past a control area in different locations of the domain. The results are shown normalized by the total number of virus copies ejected during a sneeze. The dimensional concentration of virus copies can be obtained by multiplying the normalized exposure data for the viral load and the ejected liquid volume (0.01mL in the present simulations). We can observe the presence of a core region characterized by a high level of virus exposure, which is mainly determined by the large droplets (100 microns or more). These droplets follow almost ballistic paths and settle to the ground within 1.25m. This core region is surrounded by a wider region characterized by a lower level of virus exposure. Although, in this outer region, the value of exposure is smaller, a susceptible individual is still exposed to thousands of virus copies (here we consider an average viral load for SARS-CoV-2 of 7×106 copies per mL). According to the independent action hypothesis, the presence of thousands of virus copies in the small droplets and droplet nuclei poses a significant threat on both the short- and long-range airborne transmission routes of SARS-CoV-2.