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Major subgroup analyses of all-cause mortality and cardiovascular mortality/HF hospitalization by VHD status. p values for interaction across subgroups were presented. Hazard ratios and 95% confidence intervals were adjusted for covariates. The prognostic value of VHD was emphasized in patients < 80 years old for both clinical outcomes, and in the absence of heart failure for prediction of cardiovascular mortality/HF hospitalization. Abbreviations as previously reported
