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. 2021 Sep 15;9:e12171. doi: 10.7717/peerj.12171

Figure 3. Associations between down-regulated CDC42EP3 and clinicopathological parameters in ovarian cancer patients.

Figure 3

(A–C) Compared to normal ovary tissues, CDC42EP3 was significantly down-regulated in ovarian cancer tissues. (D–F) qPCR and western blot were used to confirm the down-regulation of CDC42EP3 expression in ovarian cancer cells A2780 and TOV112D compared with the normal ovarian epithelial cell IOSE80. (G) Association of CDC42EP3 level with tumor grade. (H–I) Kaplan–Meier curves was conducted to explore the roles of CDC42EP3 expression on the OS in low-grade and high-grade ovarian cancer patients.