Table 3.

The Antimicrobial Resistance of Invasive K. pneumoniae Strains in This Study

Antibiotics	Total	CRHV-KP	non CRHV-KP	P value
	(n=94)	(n=12)	(n=82)
	R (n, %)	R (n, %)	R (n, %)
Aminoglycosides
Gentamicin	35 (37.23)	2 (16.67)	33 (40.24)	0.2083
Amikacin	2 (2.13)	2 (16.67)	0 (0)	0.0151
Tobramycin	28 (29.79)	2 (16.67)	26 (31.71)	0.4677
Carbapenems
Meropenem	12 (12.77)	12 (100.00)	0 (0)	2.6496E-20
Imipenem	12 (12.77)	12 (100.00)	0 (0)	2.6496E-20
Ertapenem	12 (12.77)	12 (100.00)	0 (0)	2.6496E-20
Non-extended spectrum cephalosporins; 1st and 2nd generation cephalosporins
Cefazolin	44 (46.81)	12 (100.00)	32 (39.02)	7.6944E-05
Cefuroxime	44 (46.81)	12 (100.00)	32 (39.02)	7.6944E-05
Extended-spectrum cephalosporins; 3rd and 4th generation cephalosporins
Cefotaxime	36 (38.30)	12 (100.00)	24 (29.27)	1.1345E-05
Ceftriaxone	41 (43.62)	12 (100.00)	29 (35.37)	2.4768E-05
Ceftazidime	22 (23.40)	12 (100.00)	10 (12.20)	2.2286E-10
Cefepime	20 (21.28)	11 (91.67)	9 (10.98)	1.9556E-09
Ceftizoxime	25 (26.60)	12 (100.00)	13 (15.85)	6.1744E-09
Cephalosporins + β-lactamase inhibitors
Cefoperazone/sulbactam	17 (18.09)	12 (100.00)	5 (6.10)	6.7846E-14
Cephamycins
Cefoxitin	22 (23.40)	11 (91.67)	11 (13.41)	1.9690E-08
Cefotetan	13 (13.83)	10 (83.33)	3 (3.66)	2.2231E-12
Fluoroquinolones
Ciprofloxacin	26 (27.66)	4 (33.33)	22 (26.83)	0.9006
Levofloxacin	4 (4.26)	2 (16.67)	2 (2.44)	0.0780
Monobactams
Aztreonam	17 (18.09)	3 (25.00)	14 (17.07)	0.7911
Penicillins + β-lactamase inhibitors
Ampicillin/sulbactam	46 (48.94)	12 (100.00)	34 (41.46)	0.0002
Piperacillin/tazobactam	12 (12.77)	10 (83.33)	2 (2.44)	1.5841E-13
Penicillins
Piperacillin	18 (19.15)	10 (83.33)	8 (9.76)	1.5374E-08
Sulfonamides
Aulfamethoxazole trimethoprim	42 (44.68)	8 (66.67)	34 (41.46)	0.1010
ESBL (+)	29 (30.85)	0 (0)	29 (35.37)	0.0321