Table 4.
The β-Lactam Antibiotic and Colistin Resistance Genes of Invasive K. pneumoniae Strains in This Study
| Total | CRHV-KP | non CRHV-KP | P value | |
|---|---|---|---|---|
| (n=94) | (n=12) | (n=82) | ||
| Carbapenemase genes, n (%) | ||||
| blaKPC-2 | 10 (10.64) | 0 (0) | 10 (12.20) | 0.4363 |
| blaOXA-1 | 5 (5.32) | 1 (8.33) | 4 (4.88) | 0.5029 |
| blaNDM-1 | 18 (19.15) | 1 (8.33) | 17 (20.73) | 0.5308 |
| blaVIM-1 | 13 (13.83) | 2 (16.67) | 11 (13.41) | 0.8864 |
| blaIMP, blaAIM, blaGIM, blaSIM, blaSPM, blaBIC, blaDIM | 0 (0) | 0 (0) | 0 (0) | 1.0000 |
| ESBL genes, n (%) | ||||
| blaTEM-1 | 18 (19.15) | 3 (25.00) | 15 (18.29) | 0.8738 |
| blaSHV-11 | 81 (86.17) | 12 (100.00) | 69 (84.15) | 0.2992 |
| blaCTX-M-14 | 46 (48.94) | 4 (33.33) | 42 (51.22) | 0.2470 |
| blaVEB-1 | 6 (6.38) | 0 (0) | 6 (7.32) | 1.0000 |
| blaPER | 0 (0) | 0 (0) | 0 (0) | 1.0000 |
| AmpC enzyme genes, n (%) | ||||
| blaACT-1 | 66 (70.21) | 12 (100.00) | 54 (65.85) | 0.0377 |
| blaDHA-1 | 30 (31.91) | 3 (25.00) | 27 (32.93) | 0.8269 |
| blaFOX-1 | 81 (86.17) | 12 (100.00) | 69 (84.15) | 0.2992 |
| blaCMY, blaACC, blaMOX, blaCIT, blaEBC | 0 (0) | 0 (0) | 0 (0) | 1.0000 |
| Colistin resistance genes, n (%) | ||||
| MCR-1 | 0 (0) | 0 (0) | 0 (0) | 1.0000 |
| MCR-2 | 0 (0) | 0 (0) | 0 (0) | 1.0000 |