Table 3.
Associations of pain symptoms and Endometriosis Health Profile-30 scales with the number of tender areas in the pelvic floor, abdomen, and uterus1,2
| Pelvic floor tender areas3 | Abdominal tender areas4 | Uterine tenderness5 | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Low Tenderness (N=44) | High Tenderness (N=44) | p-value6 | Low Tenderness (N=51) | High Tenderness (N=37) | p-value6 | Low Tenderness (N=37) | High Tenderness (N=51) | p-value6 | |
| Duration of pain (years) | 4.50 (0–29) | 4.50 (0–20) | 0.71 | 3.50 (0–26) | 5.00 (0.83–29.0) | 0.09 | 2.00 (0–29) | 5.00 (0.83–23) | 0.04 |
| Endometriosis Health Profile-30 | |||||||||
| Pain | 9.09 (0–56.8) | 38.6 (0–75.0) | <0.001 | 13.6 (0–68.2) | 38.6 (0–75.0) | <0.001 | 4.55 (0–68.2) | 40.9 (0–75.0) | <0.001 |
| Control and helplessness | 4.17 (0–91.7) | 50.0 (0–95.8) | <0.001 | 16.7 (0–91.7) | 50.0 (0–95.8) | <0.001 | 0 (0–83.3) | 50.0 (0–95.8) | <0.001 |
| Emotion | 4.17 (0–58.3) | 33.3 (0–79.2) | <0.001 | 8.33 (0–62.5) | 29.2 (0–79.2) | 0.004 | 0 (0–62.5) | 33.3 (0–79.2) | <0.001 |
| Social | 6.25 (0–81.3) | 37.5 (0–100) | 0.001 | 6.25 (0–75.0) | 37.5 (0–100) | 0.002 | 6.25 (0–68.8) | 37.5 (0–100) | <0.001 |
| Self-image | 8.33 (0–75) | 41.7 (0–83.3) | <0.001 | 16.7 (0–75.0) | 50.0 (0–83.3) | <0.001 | 0 (0–58.3) | 41.7 (0–83.3) | <0.001 |
| Dysmenorrhea | |||||||||
| None/mild | 15 (35.7) | 1 (2.3) | <0.001 | 16 (32.0) | 0 (0.0) | <0.001 | 14 (37.8) | 2 (4.1) | <0.001 |
| Moderate/Severe | 27 (64.3) | 43 (97.7) | 34 (68.0) | 36 (100) | 23 (62.2) | 47 (95.9) | |||
| Dysuria | |||||||||
| None/mild | 39 (92.9) | 37 (84.1) | 0.31 | 44 (88.0) | 32 (88.9) | 0.99 | 34 (94.4) | 42 (84.0) | 0.18 |
| Moderate/Severe | 3 (7.1) | 7 (15.9) | 6 (12.0) | 4 (11.1) | 2 (5.6) | 8 (16.0) | |||
| Dyschezia | |||||||||
| None/mild | 30 (71.4) | 24 (54.5) | 0.11 | 33 (66.0) | 21 (58.3) | 0.47 | 28 (77.8) | 26 (52.0) | 0.01 |
| Moderate/Severe | 12 (28.6) | 20 (45.5) | 17 (34.0) | 15 (41.7) | 8 (22.2) | 24 (48.0) | |||
| Dyspareunia (deep pain) | |||||||||
| None/mild | 26 (63.4) | 9 (21.4) | <0.001 | 29 (59.2) | 6 (17.6) | <0.001 | 24 (68.6) | 11 (22.9) | <0.001 |
| Moderate/Severe | 15 (36.6) | 33 (78.6) | 20 (40.8) | 28 (82.4) | 11 (31.4) | 37 (77.1) | |||
| Dyspareunia (pain with entry) | |||||||||
| None/mild | 35 (85.4) | 23 (54.8) | 0.002 | 40 (83.3) | 18 (51.4) | 0.002 | 32 (91.4) | 26 (54.2) | <0.001 |
| Moderate/Severe | 6 (14.6) | 19 (45.2) | 8 (16.7) | 17 (48.6) | 3 (8.6) | 22 (45.8) | |||
| McGill Present Pain Intensity | |||||||||
| No/mild pain | 31 (73.8) | 12 (27.3) | <0.001 | 36 (72.0) | 7 (19.4) | <0.001 | 30 (81.1) | 13 (26.5) | <0.001 |
| Discomforting/distressing pain | 8 (19.1) | 24 (54.5) | 12 (24.0) | 20 (55.6) | 7 (18.9) | 25 (51.0) | |||
| Horrible/excruciating pain | 3 (7.1) | 8 (18.2) | 2 (4.0) | 9 (25.0) | 0 (0.0) | 11 (22.5) | |||
Data are given as median (range) for continuous variables and sample size (percentage) for categorical variables.
Sample size is 86 for pain duration, dysmenorrhea, dysuria, dyschezia, and McGill present pain intensity; sample size is 83 for dyspareunia (deep pain) and dyspareunia (pain with entry); sample size is 80 for Endometriosis Health Profile-30 scales
Pelvic floor tender areas assessed at right/left pubococcygeus, right/left iliococcygeus, and right/left coccygeus. Each area reported as tender was palpated with 2kg of pressure and a 0–10 pain rating was obtained. High tenderness defined as >2 areas with pain rating of ≥4 on 0–10 scale (moderate/severe pain).
Abdominal tender areas assessed at right/left upper and right/left lower abdominal, suprapubic and umbilical areas. High tenderness defined as >1 tender area reported as tender.
Uterine tenderness assessed at posterior lower uterine segment with single digit vaginal exam. Participants with uterine tenderness had 2kg of pressure applied to the area and reported a 0–10 pain rating. High tenderness was defined as uterine tenderness with a pain rating of ≥4 on 0–10 scale (moderate/severe pain).
Two-sided probability values from Chi-square or Fisher’s exact test for categorical variables and from Wilcoxon Rank Sum for continuous variables