Table 3.

State-arrival-extended Cox-Markov multivariate model’s transition HRs (95% CI) as a function of ACEIs/ARBs

Transition		ACEIs/ARBs’ use
		Model 1	P value	Model 2	P value
1	Admission → Severity	1.15 (0.98 to 1.36)	0.092	1.10 (0.88 to 1.36)	0.409
2	Admission → Recovery	1.07 (1.01 to 1.13)	0.027	1.05 (0.98 to 1.13)	0.182
3	Admission → Death	0.83 (0.75 to 0.93)	0.001	0.80 (0.70 to 0.91)	0.001
4	Severity → Recovery	1.16 (0.97 to 1.38)	0.098	1.16 (0.93 to 1.45)	0.195
5	Severity → Death	0.91 (0.73 to 1.13)	0.381	1.11 (0.83 to 1.49)	0.485

Model 1: adjusted for gender, age (years), prevalent CVD, HBP, DM and time (days) to severity and model 2: further by prevalent obesity and cognitive issues.

ACEIs/ARBs, ACE inhibitors /angiotensin receptor blockers; CVD, cardiovascular disease; DM, diabetes mellitus; HBP, high blood pressure.