Table 1.
Baseline characteristics by glucose response curve shape
| All | Monophasic | Biphasic | Continuous rise | Overall p value | M vs B | M vs C | B vs C | |
| P value | P value | P value | ||||||
| n | 3108 | 2107 | 172 | 829 | ||||
| Female (%) | 1124 (36.2) | 645 (30.6) | 71 (41.3) | 408 (49.2) | <0.001 | 0.005 | <0.001 | 0.070 |
| Age (years) | 56.6 (10.0) | 56.0 (9.9) | 57.0 (10.9) | 58.1 (9.9) | <0.001 | 0.216 | <0.001 | 0.249 |
| Age (years) (%) | <0.001 | 0.048 | <0.001 | 0.242 | ||||
| 22–50 | 835 (26.9) | 602 (28.6) | 49 (28.5) | 184 (22.2) | ||||
| >50–60 | 1095 (35.2) | 757 (35.9) | 49 (28.5) | 289 (34.9) | ||||
| >60–70 | 970 (31.2) | 637 (30.2) | 58 (33.7) | 275 (33.2) | ||||
| >70–85 | 207 (6.7) | 110 (5.2) | 16 (9.3) | 81 (9.8) | ||||
| Race (%) | <0.001 | 0.080 | <0.001 | 0.139 | ||||
| American Indian/Alaska Native | 103 (3.3) | 73 (3.5) | 8 (4.7) | 22 (2.7) | ||||
| Asian | 119 (3.8) | 75 (3.6) | 13 (7.6) | 31 (3.7) | ||||
| Hawaiian/Pacific Islander | 20 (0.6) | 17 (0.8) | 1 (0.6) | 2 (0.2) | ||||
| African American/black | 553 (17.8) | 330 (15.7) | 34 (19.8) | 189 (22.8) | ||||
| White | 2084 (67.1) | 1466 (69.6) | 107 (62.2) | 515 (62.1) | ||||
| Other/multiple | 189 (6.1) | 121 (5.7) | 8 (4.7) | 60 (7.2) | ||||
| Unknown/not reported | 40 (1.3) | 29 (1.4) | 1 (0.6) | 10 (1.2) | ||||
| Hispanic (%) | 611 (19.8) | 391 (18.7) | 34 (19.9) | 186 (22.7) | 0.053 | 0.780 | 0.018 | 0.484 |
| Anthropometrics | ||||||||
| Weight (kg) | 99.6 (22.1) | 103.2 (22.4) | 93.6 (21.8) | 91.4 (19.0) | <0.001 | <0.001 | <0.001 | 0.216 |
| BMI (kg/m2) | 34.2 (6.7) | 34.9 (6.8) | 32.5 (6.4) | 32.5 (6.0) | <0.001 | <0.001 | <0.001 | 0.904 |
| Waist circumference (cm) | 112.2 (15.7) | 114.4 (15.6) | 108.8 (18.1) | 107.3 (14.3) | <0.001 | <0.001 | <0.001 | 0.306 |
| Duration of diabetes (years) | 4.0 (2.8) | 3.9 (2.7) | 4.3 (2.8) | 4.3 (2.8) | 0.006 | 0.108 | 0.004 | 0.907 |
| Metformin dose (mg/day) (%) | 0.001 | 0.040 | <0.001 | 0.478 | ||||
| 1000 | 107 (3.4) | 60 (2.8) | 6 (3.5) | 41 (4.9) | ||||
| 1500 | 125 (4.0) | 70 (3.3) | 12 (7.0) | 43 (5.2) | ||||
| 2000 | 2876 (92.5) | 1977 (93.8) | 154 (89.5) | 745 (89.9) | ||||
| eGFR (mL/min/1.73 m2) | 95.4 (16.9) | 95.7 (16.6) | 95.8 (7.6) | 94.8 (17.4) | 0.414 | 0.913 | 0.204 | 0.478 |
Mean (SD).
B, biphasic shape; BMI, body mass index; C, continuous rise shape; eGFR, estimated glomerular filtration rate; M, monophasic shape.