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. Author manuscript; available in PMC: 2022 Apr 7.
Published in final edited form as: J Am Chem Soc. 2021 Mar 29;143(13):5011–5021. doi: 10.1021/jacs.0c13164

Figure 2. End-point coupling product distributions in the presence and absence of PhDIR.

Figure 2.

Couplings of equimolar (a) 1 and 10, (b) 1 and 11, (c) 1 and 6 and (d) 1 and 8. Total content of the three coupling product types for each reaction was estimated by summing up peak integrations of the corresponding ion species (m/z of [M-H2O+H]+) detected by LC-MS, and each coupling product composition (type and coupling mode) was normalized to the total integrations. Values reflect only relative product concentrations to compare reactions. Colors indicate reactions carried out with empty vector control (black, on the left) or PhDIR (blue, on the right) extracts. Filled, slash-patterned columns indicate levels of 8-8’ coupling products. Bar heights indicate the mean of triplicates, and error bars show standard deviations.