Table 2.
Clinical evidence of TCM for typical characteristics of COVID-19.
| Clinical evidence | TCM |
|---|---|
| Clinical symptom | |
| Fever | Jinhua Qinggan granules37, Lianhua Qingwen capsule27,28,38, 39, 40, Qingfei Paidu decoction46,47, Xuanfei Baidu decoction32, Shufeng Jiedu capsule52,53, Lianhua Qingke granules56, Toujie Quwen granules57, Reyanning mixture58, Maxing Shigan decoction59, Qingfei Dayuan granules63, Xuanfei Huazhuo decoction65, Qingfei Touxie Fuzheng recipe67, Diammonium glycyrrhizinate70 |
| Cough | Jinhua Qinggan granules37, Lianhua Qingwen capsule27,38, 39, 40, Qingfei Paidu decoction46,47, Xuanfei Baidu decoction32, Shufeng Jiedu capsule51, 52, 53, Lianhua Qingke granules56, Toujie Quwen granules57, Reyanning mixture58, Maxing Shigan decoction59, Qingfei Dayuan granules63, Xuanfei Huazhuo decoction65, Qingfei Touxie Fuzheng recipe67, Matrine injection69, Diammonium glycyrrhizinate70 |
| Fatigue | Jinhua Qinggan granules37, Lianhua Qingwen capsule27,28,39,40, Qingfei Paidu decoction46, Xuanfei Baidu decoction32, Shufeng Jiedu capsule51,53, Lianhua Qingke granules56, Toujie Quwen granules57, Reyanning mixture58, Maxing Shigan decoction59, Qingfei Dayuan granules63, Xuanfei Huazhuo decoction65, Matrine injection69, Diammonium glycyrrhizinate70 |
| Dry throat | Lianhua Qingwen capsule39, Shufeng Jiedu capsule53, Lianhua Qingke granules56, Toujie Quwen granules57, Reyanning mixture58 |
| Sore throat | Lianhua Qingwen capsule39, Lianhua Qingke granules56, Toujie Quwen granules57, Qingfei Dayuan granules63 |
| Sputum production | Jinhua Qinggan granules37, Qingfei Paidu decoction49, Lianhua Qingke granules56, Xuanfei Huazhuo decoction65, Qingfei Touxie Fuzheng recipe67 |
| Shortness of breath | Lianhua Qingwen capsule28,38, Qingfei Paidu decoction46, Shufeng Jiedu capsule51,52, Qingfei Dayuan granules63, Qingfei Touxie Fuzheng recipe67 |
| Myalgia | Lianhua Qingwen capsule28, Shufeng Jiedu capsule53, Qingfei Dayuan granules63 |
| Diarrhea | Lianhua Qingwen capsule28, Shufeng Jiedu capsule53, Maxing Shigan decoction59, Xuanfei Huazhuo decoction65 |
| Duration of nucleic acid turn negative | Jinhua Qinggan granules36, Lianhua Qingwen capsule41, Qingfei Paidu decoction48, Shufeng Jiedu capsule53, Reyanning mixture58, Honeysuckle oral liquid60, “Fei Yan No. 1”64, Matrine injection69 |
| Time to symptom recovery | Lianhua Qingwen capsule27, Xuebijing injection44, Qingfei Paidu decoction47, 48, 49, 50, Huashi Baidu Decoction31, Honeysuckle oral liquid60, Yidu-toxicity blocking lung decoction62, “Fei Yan No. 1”64, Keguan-166 |
| The progression to severe disease | Shufeng Jiedu capsule51, Hanshiyi formula55 |
| Multiorgan injury | Xuebijing injection44, Qingfei Paidu decoction48 |
| Lung feature | |
| Lung inflammatory absorption | Jinhua Qinggan granules36, Lianhua Qingwen capsule41, Xuebijing injection44, Qingfei Paidu decoction45, Shufeng Jiedu capsule52, “Fei Yan No. 1”64, Xuanfei Huazhuo decoction65, Ganlu Xiaodu decoction68, Matrine injection69 |
| CT imaging | Lianhua Qingwen capsule27, Qingfei Paidu decoction46,47, Huashi Baidu formula30, Shufeng Jiedu capsule51, Toujie Quwen granules57, Reyanning mixture58, Honeysuckle oral liquid60 |
| Lung injury | Xuebijing injection42, Lianhua Qingke granules56, Qingfei Dayuan granules63, Keguan-166 |
| Lung function | Chansu injection61 |
| Laboratory finding | |
| WBC count | Jinhua Qinggan granules36, Lianhua Qingwen capsule39, Xuebijing injection43,44, Xuanfei Baidu decoction32, Shufeng Jiedu capsule54, “Fei Yan No. 1”64, Xuanfei Huazhuo decoction65, Ganlu Xiaodu decoction68 |
| Lymphocyte count | Jinhua Qinggan granules36, Lianhua Qingwen capsule39,41, Xuebijing injection43,44, Qingfei Paidu decoction45,46, Xuanfei Baidu decoction32, Shufeng Jiedu capsule51, Toujie Quwen granules57, Qingfei Dayuan granules63, Xuanfei Huazhuo decoction65, Ganlu Xiaodu decoction68, Matrine injection69, Diammonium glycyrrhizinate70 |
| Oxygenation index | Xuebijing injection43, Chansu injection61 |
| CRP | Lianhua Qingwen capsule39, Xuebijing injection43,44, Qingfei Paidu decoction45, Xuanfei Baidu Decoction32, Huashi Baidu formula30, Shufeng Jiedu capsule51,54, Toujie Quwen granules57, Maxing Shigan decoction59, Qingfei Dayuan granules63, “Fei Yan No. 1”64, Xuanfei Huazhuo decoction65, Qingfei Touxie Fuzheng recipe67, Matrine injection69, Diammonium glycyrrhizinate70 |
| IL-6 | Xuebijing injection42, Qingfei Paidu decoction48, Shufeng Jiedu capsule54, Yidu-toxicity blocking lung decoction62, Qingfei Touxie Fuzheng recipe67, Diammonium glycyrrhizinate70 |
| TNF-α | Xuebijing injection42, Yidu-toxicity blocking lung decoction62 |
| ESR | Xuebijing injection44, Qingfei Paidu decoction46, Xuanfei Baidu Decoction32, Huashi Baidu formula30, Xuanfei Huazhuo decoction65, Qingfei Touxie Fuzheng recipe67, Diammonium glycyrrhizinate70 |
| CK | Qingfei Paidu decoction45 |
| LDH | Qingfei Paidu decoction45, Xuanfei Huazhuo decoction65 |
| ALT | Qingfei Paidu decoction46, Xuanfei Huazhuo decoction65 |
| AST | Qingfei Paidu decoction46, Xuanfei Huazhuo decoction65 |
| Procalcitonin | Lianhua Qingwen capsule39, Shufeng Jiedu capsule51, Toujie Quwen granules57, Qingfei Dayuan granules63, Diammonium glycyrrhizinate70 |
| D-dimer | Qingfei Paidu decoction46, Shufeng Jiedu capsule51, Toujie Quwen granules57 |
| CD4+ T cell | Maxing Shigan decoction59 |
| CD8+ T cell | Maxing Shigan decoction59 |